Table 1 Patient characteristics of three sets
Variables | Training set (n = 562) | P value | External test set 1 (n = 510) | P value | External test set 2 (n = 113) | P value | |||
---|---|---|---|---|---|---|---|---|---|
Non-IDH wt with TERTp-mut (n = 392) | IDH wt with TERTp-mut (n = 170) | Non-IDH wt with TERTp-mut (n = 478) | IDH wt with TERTp-mut (n = 32) | Non-IDH wt with TERTp-mut (n = 95) | IDH wt with TERTp-mut (n = 18) | ||||
Age(years) | 47.10 ± 15.90 | 55.18 ± 11.88 | <0.001* | 43.21 ± 12.02 | 42.47 ± 11.42 | 0.650 | 43.95 ± 13.53 | 57.17 ± 7.42 | <0.001* |
Sex | 0.926 | 1 | 1 | ||||||
Male | 197(50.26%) | 84(49.41%) | 174(36.40%) | 12(37.50%) | 48(50.53%) | 9(50.00%) | |||
Female | 195(49.74%) | 86(50.59%) | 304(63.60%) | 20(62.50%) | 47(49.47%) | 9(50.00%) | |||
WHO grades | <0.001* | 0.004* | 0.004* | ||||||
2 | 137(34.95%) | 26(15.29%) | 294(61.51%) | 15(46.88%) | 48(50.53) | 2(11.11) | |||
3 | 134(34.18%) | 33(19.41%) | 130(27.20%) | 7(21.88%) | 47(49.47%) | 16(88.89%) | |||
4 | 121(30.87%) | 115(67.65) | 54(11.30%) | 10(31.25%) | null | null |