Fig. 1: The association of lifestyle factor, class and score with depression risk.

We utilized participants (n = 287,282) from UKB with completed lifestyle factor assessments in the survival analyses. The upper panel presents the association of lifestyle factors with depression. The bottom panel presents the association of a per-one-point increment in healthy lifestyle score with depression. The middle panel presents the association between each class of lifestyle and depression, with each lifestyle score reclassified into three classes (favorable scoring 5 to 7, intermediate scoring 2 to 4 and unfavorable scoring 0 to 1). All these models were adjusted for age, sex, Townsend deprivation index, BMI and education level. Two-sided unadjusted association P values from multivariate Cox models are given. Data are presented as mean values ± s.e.m. The widths of the lines extending from the center points represent 95% CI.