Fig. 4: Association of lifestyle with brain structure and peripheral markers. | Nature Mental Health

Fig. 4: Association of lifestyle with brain structure and peripheral markers.

From: The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression

Fig. 4

a, A total of 32,839 participants were utilized in the correlation analyses between lifestyle and brain structural imaging. Significant associations between lifestyle scores and brain volumes were adjusted for age, sex, BMI, Townsend deprivation index, education levels, neuroimaging scanning sites and estimated total intracranial volume after FDR correction (α = 0.05). b, Associations of lifestyle with peripheral markers, adjusted for age, sex, BMI, Townsend deprivation index and education level. As the different biomarkers have different sample sizes, we list the sample size corresponding to each specific biomarker in the full correlation results tables (Supplementary Tables 18 and 19). The height, color and size of each data point indicate the Pearson correlation value (r) between the lifestyle score and one marker. The horizontal dashed line denotes the positive and negative correlation boundary. NS, not significant. HDL High-Density Lipoprotein, VLDL Very-Low-Density Lipoprotein.

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