Table 1 Characteristics of pregnant people with any laboratory evidence of Zika virus infection and a subset with nucleic acid amplification test (NAAT)-confirmed Zika virus infection, U.S. Zika Pregnancy and Infant Registry, U.S. States and DC.

From: Outcomes up to age 36 months after congenital Zika virus infection—U.S. states

 

Total n (%) N = 2377

NAAT-confirmed n (%) N = 423

Maternal age (years)

2347

421

Median (IQR)

27 (22–32)

27 (22–32)

 <20

307 (13.1)

55 (13.1)

 20–24

507 (21.6)

91 (21.6)

 25–29

620 (26.4)

113 (26.8)

 30–34

518 (22.1)

92 (21.9)

 35–39

317 (13.5)

54 (12.8)

 ≥40

78 (3.3)

16 (3.8)

Unknown/Not Reported

30 (1.3)

2 (0.5)

Delivery type

1737

272

 Vaginal

1141 (65.7)

177 (65.1)

 Cesarean section

596 (34.3)

95 (34.9)

Unknown/Not Reported

641 (27.0)

151 (35.7)

Plurality

2248

371

 Singleton

2212 (98.4)

366 (98.7)

 Multiple

36 (1.6)

5 (1.3)

Unknown (lost to follow-up)

0

0

Trimester with first evidence of Zika exposurea

2106

391

 First (<14 weeks)

819 (38.9)

162 (41.4)

 Second (14–27 weeks)

800 (38.0)

171 (43.7)

 Third (≥28 weeks)

487 (23.1)

58 (14.8)

Unknown/Not reported

271 (11.4)

32 (7.6)

Symptoms reportedb

653

235

 Rash

526 (80.6)

213 (90.6)

 Fever

285 (43.6)

92 (39.1)

 Joint pain

289 (44.3)

105 (44.7)

 Conjunctivitis

172 (26.3)

69 (29.4)

 Headache

27 (4.1)

10 (4.3)

 Myalgia

36 (5.5)

8 (3.4)

 Otherc

10 (1.5)

5(2.2)

  1. NAAT nucleic acid amplification test, IQR interquartile range.
  2. aSymptom onset date, travel dates to endemic region, or date of earliest laboratory evidence of Zika virus infection were used to calculate trimester of exposure.
  3. bNot mutually exclusive.
  4. cOther symptoms reported to USZPIR are chills/rigors, flu-like symptoms, diarrhea, eye pain, and nausea or vomiting.