Table 3 Clinical and biochemical parameters in PA patients with and without AAC

Parameters	PA with AAC	PA without AAC	P value
Demographic
Age (years)	53.73 ± 7.82	46.62 ± 8.01	<0.001
Sex (male%)	32 (62.7%)	58 (56.86%)	0.373
BMI (kg/m²)	26.43 ± 2.90	26.61 ± 4.70	0.777
Duration of hypertension (years)	8.00 (4.00, 10.00)	5.00 (1.00, 10.00)	0.033
SBP (mmHg)	147.27 ± 16.86	149.15 ± 18.15	0.544
DBP (mmHg)	88.18 ± 12.86	91.52 ± 13.99	0.164
AC (cm)	98.47 ± 13.93	94.56 ± 12.26	0.049
Biochemical characteristics
PAC (ng/dl)	23.97 ± 6.22	18.46 ± 6.01	<0.001
PRA (ng/ml/h)	0.46 ± 0.17	0.59 ± 0.45	0.010
ARR (ng/dL: ng/mL h)	56.53 ± 35.38	41.84 ± 32.14	0.011
Serum K⁺ (mmol/L)	3.43 ± 0.36	3.58 ± 0.38	0.022
Serum Ca²⁺ (mmol/L)	2.32 ± 0.14	2.30 ± 0.13	0.499
Phosphorus (mmol/L)	1.14 ± 0.18	1.07 ± 0.17	0.036
FPG (mmol/L)	4.71 ± 0.90	4.74 ± 0.99	0.855
TG (mmol/L)	1.75 ± 0.96	1.65 ± 0.81	0.172
TC (mmol/L)	3.96 ± 1.09	4.20 ± 0.90	0.527
HDL-C (mmol/L)	0.96 ± 0.16	0.98 ± 0.23	0.606
LDL-C (mmol/L)	2.32 ± 1.09	2.56 ± 0.80	0.130
eGFR (ml/min/1.73 m²)	98.87 ± 18.09	102.99 ± 20.62	0.234
PTH (pg/ml)	70.62 ± 16.41	52.35 ± 30.04	0.001
25-(OH)D (ng/ml)	19.80 ± 7.39	19.22 ± 8.99	0.749
Unilateral PA (%)	60.78%	42.85%	0.036

The parameters were evaluated using univariate analyses. Data are expressed as means ± SDs
eGFR = 186 × (serum creatinine)^−1.154 × (age)^−0.203 × (0.742 if female)
AAC abdominal aortic calcification, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, AC Abdominal circumference, PAC plasma aldosterone concentration, PRA plasma rennin activity, ARR aldosterone to renin (PRA) ratio, FPG fasting plasma glucose, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C lowdensity lipoprotein cholesterol, eGFR estimated glomerular fifiltration rate, PTH parathyroid hormone
Bold values indicate statistical significance p < 0.05

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