Fig. 2: Cryo-EM structure of the homotrimeric SaHerA. | Nature Communications

Fig. 2: Cryo-EM structure of the homotrimeric SaHerA.

From: Mechanistic basis for the allosteric activation of NADase activity in the Sir2-HerA antiphage defense system

Fig. 2

a Cryo-EM density maps of the trimeric SaHerA from different views. b Ribbon diagram of the structure of the homotrimeric SaHerA from the same views as in (a). c Structure of SaHerA generated by AlphaFold; the HAS ___domain, ATPase ___domain and helical bundle are colored orange, cyan and blue, respectively. d The portions discernible in the apo SaHerA structure are boxed. e, f Detailed interactions among the protomers mediated by the helical-bundle ___domain of SaHerA.

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