Extended Data Fig. 7: Nociceptive neurons regulated the number and function of gastric CAFs.
From: Nociceptive neurons promote gastric tumour progression via a CGRP–RAMP1 axis
(a) Representative images and (b) quantification of Pdgfra+ CAFs in orthotopic tumours (n = 5 mice/group). Scale bar, 100 μm. (c) Flow chart of gastric CAFs isolation. (d) Proliferation curve of gastric CAFs (n = 3 mice/group). (e) Expression levels of CAF-associated cytokines in gastric CAFs treated with vehicle of CGRP (n = 3 mice/group). Data represent mean ± SEM, and P values were calculated by t test in b and e. The statistical tests were two-sided.
