Extended Data Fig. 9: WHRadjBMI GWAS and ZNRF3 eQTL conditional signal plots. | Nature Genetics

Extended Data Fig. 9: WHRadjBMI GWAS and ZNRF3 eQTL conditional signal plots.

From: Adipose tissue eQTL meta-analysis highlights the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits

Extended Data Fig. 9

LocusZoom plots for WHRadjBMI signal 1 conditioned on signal 2 (top left) and WHRadjBMI signal 2 conditioned on signal 1 (bottom left). Plots for ZNRF3 signal 1 conditioned on signal 2 (top right) and ZNRF3 signal 2 conditioned on signal 1 (bottom right). The dots are colored by LD with the lead variant. Both plots are colored by the GWAS lead variant represented by a purple diamond. ‘AB1’ indicates all-but-one. Significance threshold for eQTLs is P ≤ 1e-6 and for GWAS is P ≤ 5e-8.

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