Fig. 6: Biopsy reclassification with genetically adjusted PSA. | Nature Genetics

Fig. 6: Biopsy reclassification with genetically adjusted PSA.

From: Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups

Fig. 6

a,b, PSA values were adjusted (Methods) using the PRS-CSx estimate from the out-of-sample discovery cohort and assessed in GERA using age-specific cutoffs in European (n = 4,736; a) and African (n = 420; b). GERA Hispanic/Latino and Asian are shown in Extended Data Fig. 3. The Sankey diagram is based on percentages of each of the flows from/into nodes. N/A, not applicable.

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