Fig. 3: Expression, splice and cell-type interaction cis-QTL mapping in whole blood. | Nature Genetics

Fig. 3: Expression, splice and cell-type interaction cis-QTL mapping in whole blood.

From: A map of blood regulatory variation in South Africans enables GWAS interpretation

Fig. 3

a, Number of genes tested (red) and significant (blue, FDR < 5%) for expression and splice cis-QTLs, stratified by gene type. b, Number of conditionally independent cis-eQTLs mapped per eGene. c, Number of significant cis-ieQTLs mapped across 21 different cell types stratified by lineage (CLP, HSC, GMP, CMP, iDC and aDC). d, Example of a cis-ieQTL for FGFR2 that is dependent on eosinophil enrichment levels (interaction term two-sided P = 2.22 × 10−13 from linear regression model).

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