Fig. 4: Sex-specific causal genes and proteins.
From: Sex differences in brain protein expression and disease
a, Causal genes with sb-pQTLs (n = 12). Among these, three also had sex-biased protein expression: CNTN2, ERLEC1 and GIGYF2 (in bold). Detailed results are in Supplementary Table 18. b, Causal proteins in females only (n = 11). Among these 11 proteins, three also had sex-biased protein expression: DOC2A, ITIH3 and DLST (in bold). c, Causal proteins in males only (n = 12). Of these 12, two also had sex-biased protein expression: CADM2 and ZZEF1 (in bold). Cross-disorder refers to major depression, bipolar disorder and schizophrenia. Asterisks indicate significant P values in the sex-specific PWAS. Detailed results are in Supplementary Table 20.
