Fig. 4: Prediction of risk of future decompensation events in advanced fibrosis using hepatic bulk RNA-seq data. | Nature Medicine

Fig. 4: Prediction of risk of future decompensation events in advanced fibrosis using hepatic bulk RNA-seq data.

From: An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease

Fig. 4

a, Correlation between the risk scores and the time of the decompensation events. b, Heatmap of the gene expression profile of the prognostic signature. c, Time-dependent ROC curves and AUC analyses by the expression of the 15 genes. d, Kaplan–Meier curves (with 95% confidence intervals) showing high- and low-risk groups for all biopsy cases; log-rank test P value < 0.0001. e, Kaplan–Meier curves demonstrating separation of patients into high- and low-risk groups in both mild (F0/1) and severe (F3/4) fibrosis stages; log-rank test P value.

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