Extended Data Fig. 1: Prevalence (as percentage) of different types of mutations identified by WGS in genes indicated for testing in the National Genomic Test Directory for Cancer (NGTDC). | Nature Medicine

Extended Data Fig. 1: Prevalence (as percentage) of different types of mutations identified by WGS in genes indicated for testing in the National Genomic Test Directory for Cancer (NGTDC).

From: Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme

Extended Data Fig. 1Extended Data Fig. 1Extended Data Fig. 1Extended Data Fig. 1

(A) Somatic small variants (single nucleotide variants (SNVs), insertions and deletions). (B) Copy-number aberrations (CNAs); onc = oncogene, tsg = tumour suppressor gene. (C) Structural variants (SVs). (D) Germline small variants related to inherited cancer risk (predisposing genes). The percentage of tumours harbouring a specific type of mutation in gene(s) indicated for testing by tumour type in the NGTDC are shown in magenta. The incidence of mutations (as a percentage) in other tumour types, not currently indicated in the NGTDC, are shown in blue. Colour gradation reflects the percentage of affected cases.

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