Extended Data Fig. 10: Conservation of biological pathways between the multi-ancestry and T2DGGI clusters. | Nature Medicine

Extended Data Fig. 10: Conservation of biological pathways between the multi-ancestry and T2DGGI clusters.

From: Multi-ancestry polygenic mechanisms of type 2 diabetes

Extended Data Fig. 10

Variants in the T2DGGI clusters (NSNP = 1,289) were assigned a proxy variant from the multi-ancestry variant set (NSNP = 650) based on linkage disequilibrium values (r2 > 0.5). The clusters were then cross-examined using a two-sided Wilcoxon rank-sum test based on the multi-ancestry bNMF variant weights.

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