Fig. 4: Proteins related to CRF whose levels are dynamic with exercise training are related to cardiometabolic risk factors and diseases. | Nature Medicine

Fig. 4: Proteins related to CRF whose levels are dynamic with exercise training are related to cardiometabolic risk factors and diseases.

From: Proteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks

Fig. 4

Heatmap of Pearson correlations between individual proteins and cardiometabolic risk factors and disease in CARDIA using the CARDIA validation sample (N = 589–669). Proteins visualized are included in the proteomic CRF score and change after a 20-week exercise intervention in HERITAGE (false discovery rate < 5%). Proteins marked with an asterisk are included in the abbreviated 21-protein score. Cells marked with an asterisk indicate Pearson correlations with false discovery rate < 5%. AAC, abdominal aorta calcification; AHA LS7, American Heart Association Life Simple 7; CAC, coronary artery calcification; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; FC, fold change; GLS, global longitudinal strain; HbA1c, hemoglobin A1c; HDL, high density lipoprotein; LV, left ventricular; PA, physical activity; SAT, subcutaneous adipose tissue; SBP, systolic blood pressure; VAT, visceral adipose tissue.

Back to article page