Fig. 2: Summary of study design.

This figure summarizes the study design, interventions, study-related visits and key study procedures. Participants could enter the study at any time point during pregnancy or postpartum (up to 12 months). As such, each individual participant could have up to seven visits if they enter the study in the first trimester of pregnancy and fewer depending on the time of study entry. AI-based screening was performed up to seven times during the study period, including during each trimester of pregnancy (first trimester, <14 weeks; second trimester, 14 to <28 weeks; and third trimester, 28 to <42 weeks and post-term) (up to three ECGs), between delivery and 6 weeks, between 6 weeks and 3 months, between 3 and 5 months, and between 5 and 12 months postpartum (up to four ECGs). Only participants in the intervention arm had a baseline echocardiogram as well as a simultaneous portable ECG recorded at each time point. AI-based prediction for LVSD using the digital stethoscope was available in real time at the point of care and 12-lead AI-ECG predictions for LVSD were provided asynchronously, usually within 1 week of ECG acquisition. *, visit 1 can vary for each participant depending on the time point at study entry in relation to delivery.