Extended Data Fig. 5: Investigating the ghrelin-induced G protein-coupling profile of the ghrelin receptor.
From: The structure and function of the ghrelin receptor coding for drug actions
(a-c) Real-time monitoring of G protein activation by the ghrelin receptor. The saturated concentration of ghrelin (10 μM) was applied at time point 0, and the change in BRET signal was monitored (a). The maximum amplitude of the response (b) and activation rates (c) are presented as bar graphs. The traces represent the mean values of three independent experiments (a). Mean ± SEM of three independent experiments is shown (b and c).
