Extended Data Fig. 2: Motif comparisons.
From: The structure and function of the ghrelin receptor coding for drug actions
A comparison of conserved motifs in structures bound to anamorelin (PDB ID: 8JSR), ghrelin (PDB ID: 7F9Y), and CPD21 (PDB ID: 6KO5). The locations of the motifs are indicated by colored boxes: magenta, salt bridge; blue, aromatic cluster; green, PI(V)F; purple, NPxxY; and red, D(E)RY. The movements of side chains that undergo significant changes upon activation of the ghrelin receptor are indicated with red arrows.
