Table 1 Demographic characteristics of the study cohort.

From: The clinical characteristics and risk factors analysis within one week before the onset of necrotizing enterocolitis

Characteristics

NEC (n = 54)

Non-NEC (n = 180)

P

Maternal characteristics

Maternal age, years, Median (P25,P75)

30.0 (27.2–32.0)

30.0 (27.0–33.2)

0.778

ART (n/N, %)

8 (14.8)

23 (12.8)

0.874

HDP (n/N, %)

10 (18.5)

55 (30.6)

0.119

Maternal diabetes (n/N, %)

15 (27.8)

40 (22.2)

0.508

Anteplacental abruption (n/N, %)

4 (7.4)

7 (3.9)

0.481

PROM > 24 h (n/N, %)

7 (13.0)

44 (24.4)

0.109

Chorioamnionitis (n/N, %)

1 (1.9)

2 (1.1)

1.000

Antenatal antibiotics (n/N, %)

14 (25.9)

55 (30.6)

0.628

Antenatal MgSO4 (n/N, %)

23 (42.6)

60 (33.3)

0.278

Antenatal steroids (n/N, %)

42 (77.8)

152 (84.4)

0.350

Delivery type-labor(n/N, %)

23 (42.6)

82 (45.6)

0.820

Singleton (n/N, %)

43 (79.6)

131 (72.8)

0.376

Infant characteristics

Female (n/N, %)

24 (44.4)

79 (43.9)

1.000

Gestational age, weeks

29.6 (2.0)

29.8 (1.86)

0.439

 ≤ 26 W (n/N, %)

3 (5.6)

10 (5.6)

1.000

 27–28 W (n/N, %)

19 (35.2)

44 (24.4)

0.166

 29–30 W (n/N, %)

21 (38.9)

82 (45.6)

0.478

 31–32 W (n/N, %)

7 (13.0)

31 (17.2)

0.593

 > 32 W (n/N, %)

4 (7.4)

13 (7.2)

0.963

BW, g, Median (P25,P75)

1175.0 (1000.0–1372.0)

1250.0 (1045.0–1400.0)

0.333

SGA (n/N, %)

14 (25.9)

39 (21.7)

0.638

Cord clamping attempted (n/N, %)

7 (13.0)

31 (17.2)

0.593

Cord milking (n/N, %)

35 (64.8)

110 (61.1)

0.740

Apgar score

 Apgar1 ≤ 3 (n/N, %)

4 (7.4)

14 (7.8)

1.000

 Apgar1:4–7 (n/N, %)

13 (24.1)

29 (16.1)

0.256

 Apgar1 > 7 (n/N, %)

37 (68.5)

137 (76.1)

0.346

 Apgar5 ≤ 7 (n/N, %)

7 (13.0)

14 (7.8)

0.369

Intensive resuscitation (n/N, %)

6 (11.1)

21 (11.7)

1,000

Stat = 1 (n/N, %)

36 (66.7)

111 (61.7)

0.613

T score, Median (P25,P75)

13.0 (6.5–13.0)

13.0 (6.0–13.0)

0.372

Temperature on admission, Median (P25,P75)

36.0 (35.8–36.2)

36.0 (35.8–36.2)

0.304

Age at onset of NEC, days, Median (P25,P75)

23.5 (16.2–29.0)

23.0 (15.0–29.0)

0.539

CGA at onset of NEC, days, Mean (SD)

232.0 (17.2)

232.0 (16.2)

0.979

  1. NEC necrotizing enterocolitis, ART assisted reproductive technology, HDP hypertension disorders of pregnancy, PROM premature rupture of membranes, BW birth weight, SGA small for gestational age, CGA corrected gestational age.