Fig. 2
From: Inhibition of Talin2 dedifferentiates myofibroblasts and reverses lung and kidney fibrosis
Increasing surface stiffnesses and pro-fibrotic conditions increase the intensity of talin2 immunostaining in human cells. (A) Freshly purified primary monocytes, and (B) immortal fibroblasts, were cultured on surfaces of increasing stiffness and in the presence of pro-fibrotic factors. n ranges from 4 to 8. * = statistical significance of P < 0.05, < 0.01, or < 0.001, Statistical comparisons are to the 12 kPa value for each dataset, 1-way ANOVA with Dunnett’s post-test, error bars are mean ± SEM. (A) and (B) are significant by ANOVA post-test for a trend between column-based datasets.
