Fig. 8 | Scientific Reports

Fig. 8

From: MYH9 promotes malignant progression of glioma cells through regulating β-catenin stability via epithelial-mesenchymal transition signaling pathway

Fig. 8

Schematic of MYH9 promoting glioma development. MYH9 bound to β-catenin and increased its protein expression by recruiting deubiquitinase USP2 to form a complex. Therefore, the degradation of β-catenin protein is inhibited and EMT signaling is finally promoted. MYH9/β-catenin/EMT is a newly discovered molecular mechanism for promoting glioma invasion.

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