Fig. 2 | Scientific Reports

Fig. 2

From: LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain

Fig. 2

The increased expression of LncRNA 4933431K23Rik in T10 spinal cord. Firstly established the rat model of SCI. (A). The expression of LncRNA49rik in T10 spinal cord was detected by qRT-PCR at 0,3,7,14 and 21 days after spinal cord injury. (B). The activation of microglia in T10 spinal cord of rats with SCI was detected by immunohistochemistry. (C).The expression of Iba-1 in T10 spinal cord of rats with SCI was detected by WB. BV2 were treated with LPS (100ng/mL) for 6h-14 days. (D). The expression of LncRNA49rik in BV2 cells was detected by qRT-PCR. E. The expression of Iba-1 protein in BV2 cells was detected by WB. NS P > 0.05,**P < 0.01, ***P < 0.001.N = 3.

Back to article page