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Multi-drug nanotherapy consistently outperforms single-drug therapy, multi-drug combination therapy, and single-drug nanotherapy across different experimental settings, therapy strategies and cancer types.
In battery research, the areas of the electrodes and cell dimensions affect the energy storage performance. Here the authors discuss the factors that influence the reliability of electrochemical measurements and battery performance in lithium-ion cells with different electrode areas.
Simulations show that two-dimensional-material-based static random-access memory (SRAM) circuits leverage their low parasitic capacitance, counteracting performance declines due to increased interconnect resistance and potentially surpassing Si-based SRAM in terms of both performance and energy efficiency at advanced technology nodes.
This analysis leverages a large-scale literature review, text mining, statistics and machine learning to identify trends, shortcomings and future opportunities in developing and deploying inorganic nanoparticles for cancer diagnosis and therapy.
While engineered nanomaterials are relatively new, organisms have been exposed to natural nanoparticles over vast periods of time. Here the authors explore the possibility that common mechanisms of response to nanomaterials may have resulted from a long evolutionary exposure history to natural nano-sized matter.
This Analysis considers the potential benefits and challenges of applying engineered nanoparticles for artificial-ocean-fertilization-driven carbon sequestration
A comprehensive analysis of the key properties of nanopesticides in controlling agricultural pests for crop enhancement shows a much higher efficacy compared with non-nano analogues, also for in-field trials.
The proposal of a FAIR-aligned Nanosafety Data Interface can advance findability, accessibility and interoperability across physicochemical, bio–nano interaction, human toxicity, omics, ecotoxicological and exposure data.
A screening-level analysis that considers system-wide benefits and costs is used to identify opportunities where engineered nanomaterials can advance the sustainability of crop-based agriculture.
Analysis of existing data on nanofertilizers and nanopesticides show that they have a gain in efficacy with respect to conventional products, but more data are necessary to evaluate all risks and benefits of using these materials in agriculture.
Analysis of the development of drug products containing nanomaterials identifies several trends as well as the relative rate of approval of these products.
This Analysis reports an environmental life-cycle screening of various nanomaterials for both batteries and fuel cells for electric vehicles, and discusses the most promising candidates for a sustainable technology.