Nature Search

Author Correction: LINE-1 transcription activates long-range gene expression

Xiufeng Li
Luyao Bie
Nian Liu
Amendments and Corrections09 Jul 2024
Nature Genetics

Volume: 56, P: 1762
The variability of DNA fingerprints in three species of swan

Anming Meng
Royston E Carter
David T Parkin
Research01 Feb 1990
Heredity

Volume: 64, P: 73-80
A Huluwa phosphorylation switch regulates embryonic axis induction

Huluwa functions as the dorsal determinant during body axis formation in vertebrates, but how it is regulated remains unclear. Here they identify a phosphorylation switch in the conserved PPNSP motif of Huluwa required for axis induction, which is targeted by multiple kinases.

Yao Li
Yun Yan
Jing Chen
ResearchOpen Access19 Nov 2024
Nature Communications

Volume: 15, P: 1-15
Author Correction: π-HuB: the proteomic navigator of the human body

Fuchu He
Ruedi Aebersold
Zemin Zhang
Amendments and Corrections23 Dec 2024
Nature

Volume: 637, P: E22
LINE-1 transcription activates long-range gene expression

A CRISPR–Cas9 screen identifies genes that modulate long interspersed nuclear element-1 (LINE-1) expression in human cells. LINE-1 5′ UTRs have enhancer features and can activate long-range gene expression, including during zygotic genome activation.

Xiufeng Li
Luyao Bie
Nian Liu
Research07 Jun 2024
Nature Genetics

Volume: 56, P: 1494-1502
Mapping the chromatin accessibility landscape of zebrafish embryogenesis at single-cell resolution by SPATAC-seq

In two independent studies, Sun, Liu et al. and Sun et al. develop SPATAC-seq to map the chromatin accessibility landscape of zebrafish embryogenesis and mouse organogenesis, respectively, and identify transcription regulators that determine cell fate.

Keyong Sun
Xin Liu
Xun Lan
Research08 Jul 2024
Nature Cell Biology

Volume: 26, P: 1187-1199
A Golgi-derived vesicle potentiates PtdIns4P to PtdIns3P conversion for endosome fission

Gong et al. uncover a role for the Golgi network in ER-associated endosome fission, showing that a Golgi-derived SEC14L2 compartment mediates ER-associated endosome fission by promoting PtdIns4P to PtdIns3P conversion.

Bo Gong
Yuting Guo
Shunji Jia
Research28 Jun 2021
Nature Cell Biology

Volume: 23, P: 782-795
Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation

Yu and colleagues report the formation of migrasomes during zebrafish gastrulation. Migrasomes provide signalling molecules to guide the migration of dorsal forerunner cells, thus controlling organ morphogenesis.

Dong Jiang
Zheng Jiang
Li Yu
Research01 Aug 2019
Nature Cell Biology

Volume: 21, P: 966-977
Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region

TGF-β signalling through SMAD transcription factors has been implicated in embryonic mesendoderm development. Liu and colleagues reveal that the Ras-regulated kinase Raf prevents excessive mesendoderm formation by phosphorylating and promoting the degradation of SMAD2.

Xingfeng Liu
Cong Xiong
Anming Meng
ResearchOpen Access16 Apr 2013
Nature Communications

Volume: 4, P: 1-11
Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis

The growth factor VEGF is known to regulate vasculogenesis but the downstream pathways activated are unclear. Here, the authors report that Sec14l3, a member of the PITP (phosphatidyl inositol transfer proteins) family regulates the formation of zebrafish vasculature by promoting VEGFR2 endocytic trafficking.

Bo Gong
Zhihao Li
Shunji Jia
ResearchOpen Access08 Apr 2019
Nature Communications

Volume: 10, P: 1-16
Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development

The morphogen, Bmp, regulates differentiation of cell fates along the ventral to dorsal axis during vertebrate embryonic development. Here, Xue et al. show that Bmp2b produced by the organizer during early gastrulation in zebrafish embryos has a role in the establishment of an appropriate Bmp morphogen activity gradient and the correct dorsoventral patterning of the embryos.

Yu Xue
Xiudeng Zheng
Anming Meng
ResearchOpen Access29 Apr 2014
Nature Communications

Volume: 5, P: 1-14
Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

It is unclear how the cytoskeleton acts to assist in TGF-β signalling downstream of the receptor. Here, in zebrafish, the authors show that the actin-bundling protein FSCN1 interacts with TGF-β type I receptors ALK 4 and 5, enabling actin filament mediated vesicle trafficking and endoderm formation.

Zhaoting Liu
Guozhu Ning
Qiang Wang
ResearchOpen Access22 Aug 2016
Nature Communications

Volume: 7, P: 1-15
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

It is unclear if there is an interaction between apical-basal (AB) polarity and planar cell polarity (PCP) pathways during morphogenesis. Here, the authors define a role for the melanoma cell adhesion molecule (MCAM), known to regulate PCP, in AB polarity via FGF signallingin vitroand in zebrafish.

Qian Gao
Junfeng Zhang
Xiyun Yan
ResearchOpen Access07 Jun 2017
Nature Communications

Volume: 8, P: 1-13
Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence

Vertebrate haematopoietic stem cells are produced from the haemogenic endothelium by an endothelial-to-haematopoietic transition. Here, the authors show that, in zebrafish and mice, this transition depends on interplay of Smad transcription factors and the ERK signalling pathway.

Chunxia Zhang
Junhua Lv
Feng Liu
Research11 Mar 2014
Nature Communications

Volume: 5, P: 1-13
π-HuB: the proteomic navigator of the human body

We introduce a major scientific endeavour called π-HuB (proteomic navigator of the human body), its aim being to generate and harness multimodality proteomic datasets to enhance our understanding of human biology.

Fuchu He
Ruedi Aebersold
Zemin Zhang
Reviews11 Dec 2024
Nature

Volume: 636, P: 322-331
Allelic reprogramming of the histone modification H3K4me3 in early mammalian development

Three papers in this issue of Nature use highly sensitive ChIP–seq assays to describe the dynamic patterns of histone modifications during early mouse embryogenesis, showing that oocytes have a distinctive epigenome and providing insights into how the maternal gene expression program transitions to the zygotic program.

Bingjie Zhang
Hui Zheng
Wei Xie
Research14 Sept 2016
Nature

Volume: 537, P: 553-557
Temporospatial inhibition of Erk signaling is required for lymphatic valve formation

Yaping Meng
Tong Lv
Shunji Jia
ResearchOpen Access11 Sept 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-17

Search

Filter By:

Search

Quick links