Despite the abundance and non-toxic nature of sodium, organosodium reagents have rarely been used in organic synthesis. Now iron-catalysed homocoupling and C(sp2)–C(sp3) cross-coupling reactions of arylsodium compounds are reported. The observed C(sp2)–C(sp3) cross-coupling reactivity of arylsodium reagents is enabled by Lewis donor additive N,N,N′,N′-tetramethylethylenediamine.
- Ikko Takahashi
- Andreu Tortajada
- Sobi Asako