Nature Search

Native diversity buffers against severity of non-native tree invasions

Analysis combining multiple global tree databases reveals that whether a ___location is invaded by non-native tree species depends on anthropogenic factors, but the severity of the invasion depends on the native species diversity.

Camille S. Delavaux
Thomas W. Crowther
Daniel S. Maynard
ResearchOpen Access23 Aug 2023
Nature

Volume: 621, P: 773-781
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Effect of climate on traits of dominant and rare tree species in the world’s forests

Species’ traits and environmental conditions determine the abundance of tree species across the globe. Here, the authors find that dominant tree species are taller and have softer wood compared to rare species and that these trait differences are more strongly associated with temperature than water availability.

Iris Hordijk
Lourens Poorter
Thomas W. Crowther
ResearchOpen Access22 May 2025
Nature Communications

Volume: 16, P: 1-15
Association between self-reported multimorbidity and longitudinal brain Aβ deposition in Alzheimer’s disease

Whether multimorbidity accelerates brain Aβ deposition in humans remains largely unknown. Here, the authors demonstrate that higher self-reported multimorbidity burden predicts increased brain Aβ accumulation rates in the ADNI cohort.

Xian-Le Bu
Wei Zhu
Kristin Fargher
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-12
Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation

In CHIP, somatic mutations in a hematopoietic stem cell lead to a clonal subpopulation of blood cells. Here, the authors perform a CHIP meta-EWAS to establish its epigenetic features and age-related outcomes.

Sara Kirmani
Tianxiao Huan
Daniel Levy
ResearchOpen Access20 May 2025
Nature Communications

Volume: 16, P: 1-14
New Fossil Hominoid Material from Uganda

DAVID ALLBROOK
W. W. BISHOP
Research23 Mar 1963
Nature

Volume: 197, P: 1187-1190
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Natural selection on protein-coding genes in the human genome

Carlos D. Bustamante
Adi Fledel-Alon
Andrew G. Clark
Research20 Oct 2005
Nature

Volume: 437, P: 1153-1157
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
A transiting giant planet in orbit around a 0.2-solar-mass host star

Analysis of data from multiple instruments reveals a giant exoplanet in orbit around the 0.2-solar-mass star TOI-6894. The existence of this exoplanetary system challenges assumptions about planet formation and it is an excellent target for atmospheric characterization.

Edward M. Bryant
Andrés Jordán
Sebastián Zúñiga-Fernández
ResearchOpen Access04 Jun 2025
Nature Astronomy

P: 1-14
An instantaneous voice-synthesis neuroprosthesis

A brain-to-voice neuroprosthesis enables a man with amyotrophic lateral sclerosis to synthesize his voice in real time by decoding neural activity, demonstrating the potential of brain–computer interfaces to enable people with paralysis to speak intelligibly and expressively.

Maitreyee Wairagkar
Nicholas S. Card
Sergey D. Stavisky
Research12 Jun 2025
Nature

P: 1-8
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A

Multiomic analysis of blast-phase myeloproliferative neoplasms identifies a chromosome 21 amplicon harboring DYRK1A as a clonal and therapeutically targetable event in around a quarter of cases.

Charlotte K. Brierley
Bon Ham Yip
Adam J. Mead
ResearchOpen Access09 Jun 2025
Nature Genetics

Volume: 57, P: 1478-1492
Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity

A population of TRAIL-positive astrocytes in glioblastoma contributes to an immunosuppressive tumour microenvironment and this mechanism can be targeted with an engineered oncolytic virus to improve outcomes.

Camilo Faust Akl
Brian M. Andersen
Francisco J. Quintana
Research21 May 2025
Nature

P: 1-11
The Earliest Hominids

DAVID PILBEAM
Research28 Sept 1968
Nature

Volume: 219, P: 1335-1338
Gravitational deflection of polarised radiation

Martin Harwit
R. V. E. Lovelace
John Broderick
Research17 May 1974
Nature

Volume: 249, P: 230-233
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Observations of a Strong Unidentified Microwave Line and of Emission from the OH Molecule

HAROLD WEAVER
DAVID R. W. WILLIAMS
W. T. LUM
Research01 Oct 1965
Nature

Volume: 208, P: 29-31
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

Polygenic risk scores for Alzheimer’s disease derived from individuals of European ancestry can show improved performance in multiancestry settings after incorporating genome-wide association summary statistics from diverse populations.

Aude Nicolas
Richard Sherva
Jean-Charles Lambert
ResearchOpen Access18 Jun 2025
Nature Genetics

P: 1-13
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

Stephen M. Hedrick
David I. Cohen
Mark M. Davis
Research08 Mar 1984
Nature

Volume: 308, P: 149-153
Origin, nature and world climate effect of Arctic Ocean ice-cover

David L. Clark
Reviews25 Nov 1982
Nature

Volume: 300, P: 321-325
Possible Identity of Miocene Tali from Kenya

DAVID PILBEAM
Research09 Aug 1969
Nature

Volume: 223, P: 648
T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

T cell responses can be generated to either pathogen infection or from priming with a vaccine. Here the authors compare T cell generation, phenotype and single cell transcriptome of participants vaccinated with a mpox vaccine or infected with the virus showing that the virus induced T cells showed more effective function and phenotype.

Ji-Li Chen
Beibei Wang
Tao Dong
ResearchOpen Access10 May 2025
Nature Communications

Volume: 16, P: 1-17
Large-scale subduction of continental crust implied by India–Asia mass-balance calculation

Buoyant continental crust is thought to resist subduction. Calculation of the crustal mass balance during the collision between India and Eurasia indicates that about 50% of pre-collisional continental crust has been subducted into the mantle.

Miquela Ingalls
David B. Rowley
Albert S. Colman
Research19 Sept 2016
Nature Geoscience

Volume: 9, P: 848-853
Small-angle scattering interferometry with neutron orbital angular momentum states

Introduction of structured neutron waves carrying orbital angular momentum (OAM) in small-angle neutron scattering experiments provides novel approaches to the characterisation of material properties. Here the authors demonstrate the retrieval of phase information in far-field intensity profiles by means of an interferometric technique using helical neutron waves.

Dusan Sarenac
Melissa E. Henderson
Dmitry A. Pushin
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-6
Nucleosome dynamics render heterochromatin accessible in living human cells

Chromatin structure is thought to regulate transcription factor access by modulating DNA accessibility. Here, the authors show that in living human cells, euchromatin and heterochromatin are fully accessible, while centromeric chromatin remains partially inaccessible.

Hemant K. Prajapati
Zhuwei Xu
David J. Clark
ResearchOpen Access16 May 2025
Nature Communications

Volume: 16, P: 1-11
Antigens of Developing Drosophila melanogaster

DAVID B. ROBERTS
Research08 Oct 1971
Nature

Volume: 233, P: 394-397
Multimode ultrastrong coupling in three-dimensional photonic-crystal cavities

Multimode ultrastrong coupling between 3D photonic-crystal cavity modes and the cyclotron resonance of a 2D electron gas reveals distinct coupling scenarios governed by the cavity’s spatial profile and potential intermode ground-state correlations.

Fuyang Tay
Ali Mojibpour
Junichiro Kono
ResearchOpen Access16 Apr 2025
Nature Communications

Volume: 16, P: 1-11
Fossil Monkeys from the Miocene of Napak, North-East Uganda

DAVID PILBEAM
ALAN WALKER
Research16 Nov 1968
Nature

Volume: 220, P: 657-660
Inertial Confinement of Extended Radio Sources

DAVID S. DEYOUNG
W. I. AXFORD
Research14 Oct 1967
Nature

Volume: 216, P: 129-131
Nucleosynthesis, neutrino bursts and γ-rays from coalescing neutron stars

David Eichler
Mario Livio
David N. Schramm
Research13 Jul 1989
Nature

Volume: 340, P: 126-128
An unusual emission-line star/X-ray source/radio star, possibly associated with an SNR

DAVID H. CLARK
PAUL MURDIN
Research02 Nov 1978
Nature

Volume: 276, P: 44-45
Balloon-borne chemiluminescent measurement of NO to 45 km

JOHN W. DRUMMOND
JAMES M. ROSEN
DAVID J. HOFMANN
Research27 Jan 1977
Nature

Volume: 265, P: 319-320
The global distribution and drivers of wood density and their impact on forest carbon stocks

Wood density is an important plant trait. Data from 1.1 million forest inventory plots and 10,703 tree species show a latitudinal gradient in wood density, with temperature and soil moisture explaining variation at the global scale and disturbance also having a role at the local level.

Lidong Mo
Thomas W. Crowther
Constantin M. Zohner
ResearchOpen Access15 Oct 2024
Nature Ecology & Evolution

Volume: 8, P: 2195-2212
Release of Hydrocyanic Acid from Crushed Tissues of all Stages in the Life-Cycle of Species of the Zygaeninae (Lepidoptera)

DAVID A. JONES
JOHN PARSONS
MIRIAM ROTHSCHILD
Research06 Jan 1962
Nature

Volume: 193, P: 52-53
Fine-scale patterns of SARS-CoV-2 spread from identical pathogen sequences

The analysis of pairs of identical SARS-CoV-2 genome sequences enables characterization of transmission patterns between geographies and age groups.

Cécile Tran-Kiem
Miguel I. Paredes
Trevor Bedford
ResearchOpen Access05 Mar 2025
Nature

Volume: 640, P: 176-185
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

The authors show that the cell-penetrating peptide DG9 enhances PMO delivery to skeletal and cardiac muscles via multiple endocytic pathways. DG9-PMO significantly boosts dystrophin restoration and cardioprotection, addressing a key challenge in the therapy of Duchenne muscular dystrophy.

Md Nur Ahad Shah
Harry Wilton-Clark
Toshifumi Yokota
ResearchOpen Access14 May 2025
Nature Communications

Volume: 16, P: 1-16
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Factor Dependent Binding of Methionyl-tRNAs to Reticulocyte Ribosomes

DAVID A. SHAFRITZ
W. FRENCH ANDERSON
Research29 Aug 1970
Nature

Volume: 227, P: 918-920
Effect of Adrenaline and Adrenergic Blocking Agents on the Basal Oxygen Consumption of the Perfused Rat Heart

DAVID R. CHALLONER
Research04 Jun 1966
Nature

Volume: 210, P: 999-1000
Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node

Combination radiotherapy (RT) + αPD-L1 enhances tumor control via a tumor-draining lymph node (TdLN)-derived CD8+ PD-1+ TCF-1+ T cells. RT + αPD-L1 induces a novel LY6A+ subset in the TdLN that migrates to the tumor and differentiates into effectors.

Yang Shen
Erin Connolly
Zachary S. Buchwald
ResearchOpen Access14 Apr 2025
Nature Communications

Volume: 16, P: 1-15
How the Cerebellum may be Used

STEPHEN BLOMFIELD
DAVID MARR
Research19 Sept 1970
Nature

Volume: 227, P: 1224-1228
Lens cytoskeleton and transparency: A model

J I Clark
J M Clark
H Matsushima
Research01 May 1999
Eye

Volume: 13, P: 417-424
Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study

The prevalence of cardiometabolic diseases (CMDs) is increasing rapidly across Africa. Here, the authors investigate autozygosity in CMD-associated traits in over 10,000 sub-Saharan African individuals, showing these traits are influenced by sex-specific inbreeding depression and environmental interactions.

Francisco C. Ceballos
Scott Hazelhurst
Michèle Ramsay
ResearchOpen Access13 Nov 2020
Nature Communications

Volume: 11, P: 1-8
Solution structure of the ets ___domain of Fli-1 when bound to DNA

Heng Liang
Xiaohong Mao
Stephen W. Fesik
Research01 Dec 1994
Nature Structural Biology

Volume: 1, P: 871-876
Passage of Antigens across the Vascular Barrier of the Thymus

KAUKO KOUVALAINEN
DAVID GITLIN
Research06 May 1967
Nature

Volume: 214, P: 592-593
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Evidence for X-ray emission from Kepler's supernova remnant

IAN R. TUOHY
JOHN J. NUGENT
DAVID H. CLARK
Research01 May 1979
Nature

Volume: 279, P: 139-140
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61

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