Impulsive behaviour characterizes several psychiatric diseases and violent behaviour but its origins are complex. Here, exon sequencing focused on fourteen serotonin- and dopamine-related genes identified a mutation in HTR2B, which was associated with psychiatric diseases marked by impulsivity in a Finnish population. The role of this serotonin receptor in impulsivity is further supported by the knockout mouse phenotype.
- Laura Bevilacqua
- Stéphane Doly
- David Goldman
