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Achieving uniform Li plating in solid-state batteries is key for their practical application. Here, the authors integrate a silver-doped lithium argyrodite layer in initially anode-free all-solid-state batteries, promoting uniform lithium plating and cell operation under a low stack pressure of 2 MPa through silver exsolution.

Disordered rock-salt positive electrodes are promising for nickel- and cobalt-free lithium-ion batteries. Here, the authors demonstrate a synthesis method that yields highly crystalline, sub-200 nm dispersed single particles, enabling improved electrochemical cycling stability.

Traditional nanopore sensors use barrel-shaped protein channels. Here, the authors report on a study into the use of globular protein, ferritin, as a nanopore sensor, demonstrating membrane insertion and sensor application, showing the potential of non-barrel-shaped proteins for nanopore sensing.

Sodium-air batteries are appealing energy storage systems due to high theoretical energy density and high sodium abundance. But they are plagued with low efficiency and large overpotential. Here, authors report long-term reversibility over 1000 cycles with 99% efficiency using a cascade electrocatalysis strategy based on Na[Li_1/3Ru_2/3]O₂ electrodes.

Zhang, Huang, Wang, Long et al. report that NAT10 enhances serine uptake and biosynthesis in an ac4C-dependent mechanism, thereby promoting stemness and progression in acute myeloid leukaemia.

To ensure the reliable operation of anode-less solid-state lithium metal battery, herein, the authors report the role of metal interlayer as the interface control strategy for achieving the stable lithium plating and stripping using the multiple operando and in-situ analysis.

Few-layer-thick 2D materials offer desirable electronic, thermal and mechanical properties, but their large-scale layer-controlled synthesis is still challenging. Here, the authors report an edge-feeding synchronous epitaxial growth method to synthesize homogeneous A3-sized graphene films with controlled thickness between 2 and 7 layers.

Dong et al. achieve Sb₂(S,Se)₃ solar cells with 10.7% efficiency by increasing charge generation with a textured electrode and reducing charge recombination and transport loss with a conformal electron-selective layer.

The powdery mildew resistance of the MLIW170/PM26 locus, which originated from wild emmer wheat, is determined by a genetically linked atypical NLR gene pair, TdCNL1 and TdCNL5, with TdCNL1 encoding an atypical nucleotide-binding leucine-rich repeat protein integrating a potassium-dependent sodium-calcium exchanger ___domain.

R9AP is a key receptor for entry of Epstein–Barr virus into human epithelial and B cells, and interacts directly with the viral glycoprotein gH/gL complex to mediate virus–host membrane fusion.

Cytoplasmic stress granules (SG) regulate cell fate and are involved in several physiological and pathological processes. Here, using mouse models of allergic rhinitis (AR), the authors reveal the formation of SGs within macrophages of the nasal mucosa and implicate SGs in the regulation of Lrp1-mediated efferocytosis and Type 2 cytokine production, aggravating AR symptoms.

DNA Damage Regulated Autophagy Modulator 1 (DRAM1) plays pivotal roles in autophagy regulation. Here, the authors show that DRAM1 stabilizes lysosomal VAMP8, thereby promoting autolysosome maturation. Furthermore, they establish that DRAM1–VAMP8 axis enhances autophagic flux and facilitates hepatocellular carcinoma extravasation, as validated in both zebrafish xenograft and mouse metastatic models.

The H9N2 avian influenza viruses (AIVs) remain dominant in live poultry markets in China, and H9N2 AIVs with HA-Q226L, PB2-V/K627 and NP-N52 mutations can be transmitted between guinea pigs and between ferrets via direct contact and respiratory droplet.

Developing safe, fast-recharging Li-metal batteries is challenging due to the need for stable, non-flammable electrolytes. This study presents an electrolyte design using miniature anion–Li⁺ solvation structures, achieving high conductivity, stable cycling and improved safety.

Using two cohorts, Liu, Ge, Xiao, Lu and colleagues perform plasma metabolomics and lipidomics, linking reduced sarcosine to sarcopenia diagnosis. In mice, they demonstrate that sarcosine enhances muscle repair, boosts adipose thermogenesis and preserves muscle mass via macrophage modulation.

Structural vacancies in crystalline solids have potential in tuning optoelectronic properties. However, the random distribution of vacancies a problem when creating materials with completely reproducible functions. Here authors use vacancy engineering to improve electronic communication between cluster units in 3D orientationally ordered MOF crystals.

A β-GalNAc-O-tyrosine glycopeptide co-assembles with Aβ42 into distinct fibrils, reducing toxic oligomers and neurotoxicity in cells and an Alzheimer’s disease mouse model, suggesting a new modality to modulate amyloid aggregation.

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

Xiao, Dong, Xie, Feng et al. developed FRα-targeting chimeras (FRTACs) for targeted membrane protein degradation by conjugating multiple folate molecules to antibodies of targeted proteins. The folate polyvalency of FRTACs enables high affinity and potency of FRTACs in eliminating target proteins.

White-light emission from materials and devices usually occurs omni-directional through space. Here, the authors show that sintering carbon dots with TiO₂ forms a microlens-shape surface that enables directional emission with 1/60 solid angle.

Dysregulated R-loops can compromise genome stability, leading to pathological consequences. Li et al. demonstrate that R-loop-induced poly(ADP-ribose) polymerase 1 activation orchestrates exonuclease 3′–5′ ___domain-containing 2-mediated R-loop resolution, thereby safeguarding genomic integrity.

The effects of non-reacting components on polyatomic reactions are still largely unclear. Here, the authors show through a combined experimental and theoretical study of the D + CH₄ reaction that the CH₃ umbrella bending mode serves as a reporter mode, revealing how the D atom dynamically approaches CH₄.

Super spreading events are considered important contributors to the spread of COVID−19, but the extent to which superspreading varies by transmission setting is unclear. Here, the authors demonstrate heterogeneity in superspreading and the generation interval between COVID−19 cases in different settings using data from Hong Kong.

Hu et al. discovered that the truncated form of human epidermal growth factor receptor 2 (HER2), called p95HER2, drives tumor progression and resistance to the antibody–drug conjugate trastuzumab deruxtecan in HER2⁺ breast cancer. Blocking p95HER2 restores antitumor immunity.

Optical frequency combs power technologies like communication but face stability issues in miniaturization. Here, authors present a self-locked microcomb in a lithium niobate chip by combining electro-optic, Kerr, and Raman effects, achieving a 300 nm span and low noise without external feedback.

Zhang et al. report the incorporation of copper halide perovskite nanocrystals into glass fibre arrays for high-resolution remote scintillation over 5 m without crosstalk. Real-time and 3D X-ray imaging are demonstrated employing 1600 densely packed fibres with a single pixel diameter of about 10.4 µm.

Epithelial malfunction is an unmet critical challenge in trachea repair. Here, Chen et al. developed a multiplexed hydrogel to promote tracheal repair with native-like epithelium in pre-clinical models, exhibiting clinical translation potential.

A versatile nano-adaptor is used to construct multi-specific nano-antibodies for treatment of tumours in mice.

A new asymmetric non-fullerene acceptor, P2EH-1V, is designed and synthesized for constructing devices demonstrating record-high efficiencies of 26.7% (certified at 26.4%) over an aperture area greater than 1 cm² in perovskite–organic tandem solar cells.

Symbolic Regression is a method for uncovering mathematical and physical relationships from data. Here, the authors propose Sym-Q, an interactive reinforcement learning-based framework with a co-design mechanism that enables efficient and guided equation discovery.

All-solid-state batteries face practical challenges such as sustainable fabrication and low-stack pressure operation. Here, authors develop a modified dry-process technique to yield robust solid electrolyte-electrode interface for practical fabrication and operation of all-solid-state batteries.

The mechanical stability of catalytic electrodes is crucial for anion exchange membrane water electrolysis. Here, the authors report a corrosion strategy to construct an electrode with high mechanical stability by anchoring a blade-shaped catalytic layer onto a dense interlayer.

The authors report a difluoroester electrolyte to enhance anion intercalation lithium metal batteries (AILMBs), improving safety and cyclability. This enables cost-effective graphitic carbon cathodes, with high durability, stability, and performance.

Fanjiang Kong, Zhixi Tian, Xingliang Hou, Baohui Liu and colleagues report the cloning and functional characterization of J, the locus underlying the long-juvenile (LJ) trait that has enabled tropical cultivation of soybean. They show that J, an ortholog of Arabidopsis ELF3, downregulates the expression of E1, thereby promoting flowering under short-day conditions.

Subcellular mRNA localization is prevalent but with poorly understood physiological roles. Here, the authors show that Net1 mRNA targeting to the basement membrane controls epithelial tissue organization and keratinocyte-stromal connections.

Lampreys are jawless vertebrates that can offer unique insights into vertebrate evolution. Here they generate a comprehensive cell atlas of the lamprey, uncovering 70 distinct cell types across 14 tissues, and identify pancreas-like cells in the lamprey small intestine.

Patients with gastric cancer often present with poor performance status, limiting both quality of life but also treatment options as they are often excluded from clinical trials. Here, the authors report a phase II trial investigating anlotinib (multi-TKI) plus toripalimab (anti-PD-L1 monoclonal antibody) in treatment-naïve advanced gastric cancer patients with performance status 2.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

The sluggish ionic conductivity of polymer electrolytes has been a long-standing concern. Here, authors present a multiscale study of the lithium ion conduction network of poly(ethylene) oxide-based electrolytes and elucidate how aluminium-oxo molecular clusters improve the transport properties.

A F-containing additive with efficient LiF contribution is urgent for Li metal batteries. The authors report a hexafluoroglutaric anhydride additive with a 91% conversion, enabling the Li metal anode with a LiF-rich interphase in regular electrolyte.

An enantioconvergent approach for direct asymmetric insertion of racemic carbon-, oxygen-, nitrogen-, sulfur- and silicon-substituted carbenoids into carbon–boron bonds is reported, enabled by a class of chiral β-amino alcohol auxiliaries. In addition, iterative asymmetric homologation offered by this method simplifies syntheses of complex molecules containing multiple stereocentres.

The diversity and genomic resources of Brassicaceae make it an ideal model for studying karyotype evolution. Here, the authors reconstruct ancestral karyotypes of Camelinodae and Brassicodae, identify cascading fusions, and highlight their stable inheritance and role in evolutionary relationships.

Ataxia-telangiectasia mutated protein (ATM) phosphorylates CD98HC to promote neutral amino acid antiporter trafficking. Here the authors show that ATM loss impairs glutamate, cystine, and arginine transport, driving metabolic stress and ataxia telangiectasia–like phenotypes.

Silicon (Si) has emerged as a promising next-generation anode material. Here the authors recycle photovoltaic waste for micro-sized Si that can pair with high-voltage cathode for high-performance Li-ion pouch cells.

Oxide ceramic electrolytes for Li-metal batteries often require high-temperature processing, which can compromise material reliability. Here, the authors present a sintering-free approach to synthesize disorder-driven garnet-type solid electrolytes, achieving performance comparable to traditional sintered materials.

The Dark sectioning algorithm removes the background and provides single-frame optical sectioning in fluorescence microscopy. It offers improved quantitative analysis and deep-tissue segmentation accuracy and is compatible to diverse modalities.

Energy density and cyclability are often a trade-off for lithium-ion batteries. The authors develop cobalt- and nickel-free cathodes with both good cycling stability and high energy density through the integration of polyanion units into rocksalt structures.

The introduction of sodium heparin passivates interface defects and enhances bonding between the electron transport layer and the perovskite layer in perovskite solar cells. The best-performing devices exhibit a certified PCE of 26.54% and maintain almost 95% of their initial performance after 1,800 h of maximum power point tracking.