Nature Search

CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

The transcription factor CREM is a pivotal regulator of NK cell function, making CREM a valuable target to increase the efficacy of anticancer immunotherapies based on this cell population and chimeric antigen receptors.

Hind Rafei
Rafet Basar
Katayoun Rezvani
ResearchOpen Access04 Jun 2025
Nature

P: 1-11
Elevated serum CA72-4 as a novel diagnostic biomarker for acute gout flares

Yong Zhuang
Xin Hu
Xinna Yang
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-6
A requirement for CARMA1 in TCR-induced NF-κB activation

Donghai Wang
Yun You
Xin Lin
Research05 Aug 2002
Nature Immunology

Volume: 3, P: 830-835
Oxidation of difluorocarbene and subsequent trifluoromethoxylation

Difluorocarbene is a versatile and efficient intermediate for fluorine incorporation. Here, the authors show that difluorocarbene can be oxidized to carbonyl fluoride and this process is confirmed in ¹⁸O-trifluoromethoxylation reactions, by observation of AgOCF₃ species and theory.

Jiao Yu
Jin-Hong Lin
Ji-Chang Xiao
ResearchOpen Access25 Nov 2019
Nature Communications

Volume: 10, P: 1-8
Supremely elastic gel polymer electrolyte enables a reliable electrode structure for silicon-based anodes

Silicon-based anodes must maintain the electrode structure to fulfil their potential. Here the authors report the use of a supremely elastic gel polymer electrolyte to stabilize such anodes at electrode and particle levels, enabling superior battery performance with a commercial-level capacity.

Qingquan Huang
Jiangxuan Song
Donghai Wang
ResearchOpen Access06 Dec 2019
Nature Communications

Volume: 10, P: 1-7
Correction: Amendments: Author Correction: A catalog of the mouse gut metagenome

Liang Xiao
Qiang Feng
Karsten Kristiansen
Amendments and Corrections03 Jan 2019
Nature Biotechnology

Volume: 37, P: 102
The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis

Fatty acid synthesis has been reported to promote glioblastoma. Here, the authors show that the tyrosine kinase c-SRC phosphorylates both acetyl-CoA synthetase ACSS2 and ATP-citrate lyase ACLY, to increase acetyl-CoA and NADPH production for fatty acid synthesis to support glioblastoma progression.

Wentao Zhao
Cong Ouyang
Zhanxiang Wang
ResearchOpen Access28 Aug 2024
Nature Communications

Volume: 15, P: 1-18
Monitoring ocean currents during the passage of Typhoon Muifa using optical-fiber distributed acoustic sensing

Using microseismic noise observed by distributed acoustic sensing (DAS) with a submarine cable, this study measures the magnitude and direction of ocean currents during the passage of typhoon Muifa and estimates the ocean wave propagation.

Jianmin Lin
Sunke Fang
Wen Xu
ResearchOpen Access06 Feb 2024
Nature Communications

Volume: 15, P: 1-10
Relationship between De Ritis and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage: Insights from the LongTEAM registry

Yonggang Ma
Fa Lin
Chao Wang
ResearchOpen Access10 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Sequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci

Castor is an important industrial oil crop, but knowledge on its genetic diversity is limited. Here, Fan et al. show geographic pattern of Chinese castors that have developed during domestication by population genetic analyses, and reveal candidate genes associated with agronomically important traits.

Wei Fan
Jianjun Lu
Peng Cui
ResearchOpen Access31 Jul 2019
Nature Communications

Volume: 10, P: 1-11
Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates

Jing-hong Chen
Ke-xin Li
Peng Luo
ResearchOpen Access15 Apr 2025
Acta Pharmacologica Sinica

P: 1-17
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

Yen-Michael S Hsu
Yongliang Zhang
Xin Lin
Research24 Dec 2006
Nature Immunology

Volume: 8, P: 198-205
Combined query embroidery image retrieval based on enhanced CNN and blend transformer

Xinzhen Zhuo
Donghai Huang
Ziyang Huang
ResearchOpen Access11 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens

Bacillus thuringiensis toxin Cry5Ba triggers potassium ion leakage, causing mitochondrial damage and energy imbalance. C. elegans can monitor this intracellular energy imbalance via AMP-activated protein kinase to trigger innate immune responses.

Shouyong Ju
Hanqiao Chen
Ming Sun
ResearchOpen Access30 Jun 2022
Communications Biology

Volume: 5, P: 1-17
A catalog of the mouse gut metagenome

The mouse gut microbiome is catalogued and compared to the human microbiome.

Liang Xiao
Qiang Feng
Karsten Kristiansen
Research28 Sept 2015
Nature Biotechnology

Volume: 33, P: 1103-1108
Molecular understanding of the self-assembly of an N-isopropylacrylamide delivery system for the loading and temperature-dependent release of curcumin

Curcumin is a natural substance with beneficial pharmacological properties, but its poor solubility, instability and poor absorption hinder its use as a therapeutic agent in the body. Here, the authors use quantum chemical calculations and molecular simulations to explore the self-assembly of N-isopropylacrylamide for its use in the loading and release of curcumin.

Qijiang Shu
Fuhua Yang
Wenping Wang
ResearchOpen Access29 Jul 2024
Communications Chemistry

Volume: 7, P: 1-13
Genetic determination in onset age of wrist fracture

Donghai Xiong
Wei Wang
Hong-Wen Deng
Research25 Apr 2007
Journal of Human Genetics

Volume: 52, P: 481-484
The performance of an integrated model including retinal information in predicting childhood hypertension

Yuan He
Shi-Ming Li
Lei Li
Research04 May 2021
Pediatric Research

Volume: 91, P: 1600-1605
LncRNA XR_596701 protects H9c2 cells against intermittent hypoxia-induced injury through regulation of the miR-344b-5p/FAIM3 axis

Qingshi Chen
Guofu Lin
Qichang Lin
ResearchOpen Access28 Jan 2022
Cell Death Discovery

Volume: 8, P: 1-11
Small-molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance

Ting Song
Yafei Guo
Zhichao Zhang
Research18 May 2021
Leukemia

Volume: 35, P: 2862-2874
Immuno-impedimetric Biosensor for Onsite Monitoring of Ascospores and Forecasting of Sclerotinia Stem Rot of Canola

Lian C. T. Shoute
Afreen Anwar
Xiujie S. Li
ResearchOpen Access17 Aug 2018
Scientific Reports

Volume: 8, P: 1-9
Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease

Zhen Zheng
Meilan Zhang
Donghai Lin
ResearchOpen Access04 Sept 2018
Scientific Reports

Volume: 8, P: 1-15
A novel serine protease, Sep1, from Bacillus firmus DS-1 has nematicidal activity and degrades multiple intestinal-associated nematode proteins

Ce Geng
Xiangtao Nie
Donghai Peng
ResearchOpen Access27 Apr 2016
Scientific Reports

Volume: 6, P: 1-12
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia

Jingshu Xu
Paul Begley
Garth J. S. Cooper
ResearchOpen Access09 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Crysalis: an integrated server for computational analysis and design of protein crystallization

Huilin Wang
Liubin Feng
Jiangning Song
ResearchOpen Access24 Feb 2016
Scientific Reports

Volume: 6, P: 1-14
Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

Longhe Yang
Long Li
Yan Qiu
ResearchOpen Access27 Aug 2015
Scientific Reports

Volume: 5, P: 1-10
CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg^−/− Mice Results in Severe Immunodeficiency

Xinru Wei
Yunxin Lai
Peng Li
ResearchOpen Access10 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

Zongyun Chen
Youtian Hu
Yingliang Wu
ResearchOpen Access08 May 2015
Scientific Reports

Volume: 5, P: 1-8
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

Lin Zhang
Dongxia Hou
Chen-Yu Zhang
Research20 Sept 2011
Cell Research

Volume: 22, P: 107-126
An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancer

Pengjun Qiu
Qiaonan Guo
Mingji Ding
ResearchOpen Access24 Dec 2022
Scientific Reports

Volume: 12, P: 1-16
Erratum: Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

Lin Zhang
Dongxia Hou
Chen-Yu Zhang
Amendments and Corrections08 Nov 2011
Cell Research

Volume: 22, P: 273-274
Structural basis of AMPK regulation by adenine nucleotides and glycogen

Xiaodan Li
Lili Wang
Karsten Melcher
ResearchOpen Access21 Nov 2014
Cell Research

Volume: 25, P: 50-66

Search

CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

Elevated serum CA72-4 as a novel diagnostic biomarker for acute gout flares

A requirement for CARMA1 in TCR-induced NF-κB activation

Oxidation of difluorocarbene and subsequent trifluoromethoxylation

Supremely elastic gel polymer electrolyte enables a reliable electrode structure for silicon-based anodes

Correction: Amendments: Author Correction: A catalog of the mouse gut metagenome

The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis

Monitoring ocean currents during the passage of Typhoon Muifa using optical-fiber distributed acoustic sensing

Relationship between De Ritis and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage: Insights from the LongTEAM registry

Sequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci

Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates

The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens

Combined query embroidery image retrieval based on enhanced CNN and blend transformer

C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens

A catalog of the mouse gut metagenome

Molecular understanding of the self-assembly of an N-isopropylacrylamide delivery system for the loading and temperature-dependent release of curcumin

Genetic determination in onset age of wrist fracture

The performance of an integrated model including retinal information in predicting childhood hypertension

LncRNA XR_596701 protects H9c2 cells against intermittent hypoxia-induced injury through regulation of the miR-344b-5p/FAIM3 axis

Small-molecule inhibitor targeting the Hsp70-Bim protein–protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance

Immuno-impedimetric Biosensor for Onsite Monitoring of Ascospores and Forecasting of Sclerotinia Stem Rot of Canola

Structural basis for the complete resistance of the human prion protein mutant G127V to prion disease

A novel serine protease, Sep1, from Bacillus firmus DS-1 has nematicidal activity and degrades multiple intestinal-associated nematode proteins

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia

Crysalis: an integrated server for computational analysis and design of protein crystallization

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

CRISPR/Cas9-Mediated Deletion of Foxn1 in NOD/SCID/IL2rg^−/− Mice Results in Severe Immunodeficiency

Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

An exosome-related long non-coding RNAs risk model could predict survival outcomes in patients with breast cancer

Erratum: Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

Structural basis of AMPK regulation by adenine nucleotides and glycogen

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