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Showing 51–100 of 6125 results
Advanced filters: Author: Eric Strong Clear advanced filters
  • This Review explores in detail the complexity of NK cell biology in humans and highlights the role of these cells in cancer immunity.

    • Eric Vivier
    • Lucas Rebuffet
    • Valeria R. Fantin
    Reviews
    Nature
    Volume: 626, P: 727-736
  • Trees come in all shapes and size, but what drives this incredible variation in tree form remains poorly understood. Using a global dataset, the authors show that a combination of climate, competition, disturbance and evolutionary history shape the crown architecture of the world’s trees and thereby constrain the 3D structure of woody ecosystems.

    • Tommaso Jucker
    • Fabian Jörg Fischer
    • Niklaus E. Zimmermann
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16
  • The bactericidal action of some antibiotics is associated with increased ATP consumption, cellular respiration, and reactive oxygen species formation. Here, Li et al. show that constitutive hydrolysis of ATP and NADH (or ‘bioenergetic stress’) potentiates the evolution of antibiotic resistance and persistence in E. coli.

    • Barry Li
    • Shivani Srivastava
    • Jason H. Yang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18
  • Understanding how RNA folds into functional structures requires methods that can systematically assess how sequence perturbations affect RNA structure and function. Here, the authors develop a broadly accessible platform for performing high-throughput cotranscriptional RNA functional assays.

    • Skyler L. Kelly
    • Eric J. Strobel
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21
  • Uechi et al. found that a small-molecule lipoamide dissolves stress granules (SGs) by targeting SFPQ, a redox-sensitive disordered SG protein, alleviating pathological phenotypes caused by amyotrophic lateral sclerosis-associated FUS and TDP-43 mutants.

    • Hiroyuki Uechi
    • Sindhuja Sridharan
    • Richard J. Wheeler
    ResearchOpen Access
    Nature Chemical Biology
    P: 1-12
  • Noel et al. show aberrant updating of expectations in three distinct mouse models of autism spectrum disorder. Brain-wide neurophysiology data suggest this stems from excess units encoding deviations from prior mean and a lack of sensory prediction errors in frontal areas.

    • Jean-Paul Noel
    • Edoardo Balzani
    • Dora E. Angelaki
    Research
    Nature Neuroscience
    P: 1-14
  • By combining modelling and simulated data with empirical data from 76 grassland sites across 6 continents, the authors show that the relative abundance of dominant species predicts species richness, while their absolute abundance predicts community biomass.

    • Pengfei Zhang
    • Eric W. Seabloom
    • Elizabeth T. Borer
    Research
    Nature Ecology & Evolution
    Volume: 9, P: 924-936
  • The Global Flourishing Study provides a comprehensive view of the distribution and determinants of well-being by assessing domains such as health, happiness, meaning, character, relationships and financial security. Initial findings reveal significant variations in flourishing across countries and demographic groups, with factors such as age, marital status and religious service attendance showing strong associations with well-being.

    • Tyler J. VanderWeele
    • Byron R. Johnson
    • George Yancey
    ResearchOpen Access
    Nature Mental Health
    Volume: 3, P: 636-653
  • Defects known as two-level systems are a major source of noise for superconducting qubits. Adding a phononic crystal is now shown to extend the lifetime of these two-level systems, which could lead to improved qubit coherence.

    • Mutasem Odeh
    • Kadircan Godeneli
    • Alp Sipahigil
    Research
    Nature Physics
    Volume: 21, P: 406-411
  • Saccadic eye movements sample the visual world, but the retinal motion they entail goes unnoticed. This study shows that lawful saccade kinematics predict motion visibility, omitting saccade-like motion while preserving sensitivity to high speed.

    • Martin Rolfs
    • Richard Schweitzer
    • Sven Ohl
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17
  • Analysis of genomic data from 981 colorectal cancers from participants in 11 countries reveals variations in mutational signatures of microsatellite-stable cancers that are dependent on geographical origin and age at which the cancer was diagnosed.

    • Marcos Díaz-Gay
    • Wellington dos Santos
    • Ludmil B. Alexandrov
    ResearchOpen Access
    Nature
    Volume: 643, P: 230-240
  • PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver and PCSK9-high cells preferring the lung.

    • Gilles Rademaker
    • Grace A. Hernandez
    • Rushika M. Perera
    Research
    Nature
    P: 1-10
  • An expert-elicitation process identifies current methodological barriers for monitoring terrestrial biodiversity, and how technological and procedural development of robotic and autonomous systems may contribute to overcoming these challenges.

    • Stephen Pringle
    • Martin Dallimer
    • Zoe G. Davies
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 9, P: 1031-1042
  • Currently, there is an urgent need to evaluate the strengths and limitations of various probe-based full transcriptome methods for formalin-fixed paraffin-embedded tumor tissues. Here, the authors analyze three commonly used methods and highlight relative advantages and disadvantages of each method in the context of operational challenges, bioinformatic analyses and biological discoveries.

    • Yixing Dong
    • Chiara Saglietti
    • Elo Madissoon
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-18
  • Neural Decomposition (NEURD) is a software package that decomposes neuronal data from high-resolution electron microscopy volumes into feature-rich graph representations to facilitate analysis for neuroscience research.

    • Brendan Celii
    • Stelios Papadopoulos
    • Jacob Reimer
    ResearchOpen Access
    Nature
    Volume: 640, P: 487-496
  • Synthesis-planning algorithms equipped with accurate knowledge of reaction rules can nowadays rival designs of expert organic chemists. This Review discusses how computer-assisted synthesis is used to help design routes that are not only chemically correct but also green, sustainable or circular.

    • Bartosz A. Grzybowski
    • Anna ŻądÅ‚o-Dobrowolska
    • Eric S. Larsen
    Reviews
    Nature Reviews Bioengineering
    P: 1-13
  • Chromosome-level genome assemblies of nine tetraploid and two diploid wild Oryza species provide insights into genome evolution within the genus Oryza and the potential for crop improvement and neodomestication.

    • Alice Fornasiero
    • Tao Feng
    • Rod A. Wing
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 1287-1297
  • An amphiphilic light-driven rotary motor is shown to form Langmuir monolayers at the air–water interface. Upon ultraviolet irradiation, the continuous rotation of the motor triggers its supramolecular polymerization and subsequent nanopatterning of the interfacial layer.

    • Philippe Schiel
    • Mounir Maaloum
    • Nicolas Giuseppone
    Research
    Nature Nanotechnology
    P: 1-10
  • Excitation of hydrogen-rich molecules often causes hydrogen migration, but characterisation of the individual sites is challenging. Here, the authors show that measurements of several isotopologues of ethanol can identify each hydrogen site’s contribution to the final products.

    • Travis Severt
    • Eleanor Weckwerth
    • Itzik Ben-Itzhak
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11
  • A connectome of the right optic lobe from a male fruitfly is presented together with an extensive collection of genetic drivers matched to a comprehensive neuron-type catalogue.

    • Aljoscha Nern
    • Frank Loesche
    • Michael B. Reiser
    ResearchOpen Access
    Nature
    Volume: 641, P: 1225-1237
  • Observations of a luminous quasar from the high-resolution spectrometer Resolve aboard XRISM revealed highly inhomogeneous wind structure outflowing from a supermassive black hole, which probably consists of up to a million clumps.

    • Marc Audard
    • Hisamitsu Awaki
    • Yerong Xu
    Research
    Nature
    Volume: 641, P: 1132-1136
  • Large language models perform well in self-interested games such as the iterated Prisoner’s Dilemma but struggle in games that require coordination. Social reasoning strategies can improve cooperative outcomes with both other models and human players.

    • Elif Akata
    • Lion Schulz
    • Eric Schulz
    ResearchOpen Access
    Nature Human Behaviour
    P: 1-11
  • Genomic studies often lack representation from diverse populations, limiting equitable insights. Here, the authors show that the BIG Initiative captures extensive genetic diversity and reveals ancestry-linked health disparities in a community-based Mid-South cohort.

    • Silvia Buonaiuto
    • Franco Marsico
    • Vincenza Colonna
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12
  • The MICrONS mouse visual cortex dataset shows that neurons with similar response properties preferentially connect, a pattern that emerges within and across brain areas and layers, and independently emerges in artificial neural networks where these ‘like-to-like’ connections prove important for task performance.

    • Zhuokun Ding
    • Paul G. Fahey
    • Andreas S. Tolias
    ResearchOpen Access
    Nature
    Volume: 640, P: 459-469
  • New treatments for cocaine use disorder (CocUD) require an understanding of the underlying neurobiology. Here, the authors show opposing effects of ZEB1 in CocUD and highlight disrupted synaptic signaling and phosphodiesterase inhibitors as potential therapeutic targets.

    • Lea Zillich
    • Annasara Artioli
    • Stephanie H. Witt
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14
  • The role of wild and domesticated animals on alpine ecosystems is unclear. Here, the authors use sedaDNA from 14 European alpine lakes to demonstrate a positive association between wild and domesticated animal and plant diversity through the past 14 thousand years.

    • Sandra Garcés-Pastor
    • Peter D. Heintzman
    • Inger Greve Alsos
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11
  • This study presents a predictive equation for total energy expenditure derived from doubly labelled water measurements. Applying this equation to two large datasets (the National Diet and Nutrition Survey and National Health and Nutrition Examination Survey) shows that the misreporting of total energy intake is greater than 50%, with important implications for macronutrient availability.

    • Rania Bajunaid
    • Chaoqun Niu
    • John R. Speakman
    ResearchOpen Access
    Nature Food
    Volume: 6, P: 58-71
  • The topological properties of twisted bilayer MoTe2 are thought to stem from a spatial texture in the layer polarization of the electronic wavefunctions. This polarization is now measured using scanning tunnelling microscopy.

    • Ellis Thompson
    • Keng Tou Chu
    • Matthew Yankowitz
    Research
    Nature Physics
    P: 1-7
  • Assessing the degree to which medical large language models reliably convey existing, trustworthy knowledge is crucial. This study introduces SourceCheckup, an automated framework revealing that large language models frequently cite medical references that do not fully support, or even contradict, their responses, showing significant gaps in reliability for clinical use.

    • Kevin Wu
    • Eric Wu
    • James Zou
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-10
  • Experiments with cold atoms in optical cavities are often limited to discontinuous operation due to reloading requirements. Now, continuous lasing is demonstrated with strontium atoms in a ring cavity, stabilized by atom loss mechanisms.

    • Vera M. Schäfer
    • Zhijing Niu
    • James K. Thompson
    ResearchOpen Access
    Nature Physics
    Volume: 21, P: 902-908
  • Here the authors identify TNIP1 as a risk factor for a fatal neurodegenerative disorder and discover specific genetic loci associated with the three main subtypes of this disorder. The findings highlight distinct disease mechanisms, emphasizing the roles of immunity and the notch signaling pathway.

    • Cyril Pottier
    • Fahri Küçükali
    • Rosa Rademakers
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19
  • South Asia is home to almost 2 billion people but is extremely underrepresented in human genetics. This study uses genomes from ~5,000 South Asians to characterize genetic variation and help facilitate future South Asian genetic studies.

    • Jeffrey D. Wall
    • J. Fah Sathirapongsasuti
    • Andrew S. Peterson
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-11
  • Wood density is an important plant trait. Data from 1.1 million forest inventory plots and 10,703 tree species show a latitudinal gradient in wood density, with temperature and soil moisture explaining variation at the global scale and disturbance also having a role at the local level.

    • Lidong Mo
    • Thomas W. Crowther
    • Constantin M. Zohner
    ResearchOpen Access
    Nature Ecology & Evolution
    Volume: 8, P: 2195-2212
  • Placenta accreta is a major complication of pregnancy that occurs when part of the placenta fails to separate normally from the uterus at delivery. In this Primer, Jauniaux et al. discuss the epidemiology, pathophysiology, diagnosis, current management options and future research areas.

    • Eric Jauniaux
    • John D. Aplin
    • Graham J. Burton
    Reviews
    Nature Reviews Disease Primers
    Volume: 11, P: 1-18
  • A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

    • Loïc Yengo
    • Sailaja Vedantam
    • Joel N. Hirschhorn
    ResearchOpen Access
    Nature
    Volume: 610, P: 704-712