Nature Search

Genetic risk factors underlying white matter hyperintensities and cortical atrophy

White matter hyperintensities are linked to cortical atrophy, a key feature in dementia. Here, the authors identify loci associated with cortical atrophy related to white matter hyperintensities, which involve vascular and neuronal processes.

Yash Patel
Jean Shin
Zdenka Pausova
ResearchOpen Access04 Nov 2024
Nature Communications

Volume: 15, P: 1-11
Ultra-high-field 7T MRI reveals changes in human medial temporal lobe volume in female adults during menstrual cycle

In this longitudinal ultra-high field neuroimaging study, Zsido et al. show the shared dynamics between the ovarian hormone fluctuations across the menstrual cycle and structural plasticity within the medial temporal lobe.

Rachel G. Zsido
Angharad N. Williams
Julia Sacher
ResearchOpen Access05 Oct 2023
Nature Mental Health

Volume: 1, P: 761-771
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Cortex morphology varies with age, cognitive function, and in neurological and psychiatric diseases. Here the authors report 160 genome-wide significant associations with thickness, surface area and volume of the total cortex and 34 cortical regions from a GWAS meta-analysis in 22,824 adults.

Edith Hofer
Gennady V. Roshchupkin
Sudha Seshadri
ResearchOpen Access22 Sept 2020
Nature Communications

Volume: 11, P: 1-16
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

An increase in the volume of the brain lateral ventricles is a sign of normal aging, but can also be associated with neurological and psychiatric disorders. Here, Vojinovic et al. identify seven genetic loci in a GWA study for ventricular volume in 23,500 individuals and find correlation with thalamus volume.

Dina Vojinovic
Hieab H. Adams
Myriam Fornage
ResearchOpen Access26 Sept 2018
Nature Communications

Volume: 9, P: 1-11
From the reward network to whole-brain metrics: structural connectivity in adolescents and young adults according to body mass index and genetic risk of obesity

Anna Prunell-Castañé
Frauke Beyer
Maite Garolera
Research25 Dec 2023
International Journal of Obesity

Volume: 48, P: 567-574
Brain-behaviour correlates of habitual motivation in chronic back pain

Frauke Nees
Michaela Ruttorf
Nicole Beyer
ResearchOpen Access06 Jul 2020
Scientific Reports

Volume: 10, P: 1-8
Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine

Nikolaus Rajewsky
Geneviève Almouzni
Frauke Zipp
Amendments and CorrectionsOpen Access17 Mar 2021
Nature

Volume: 592, P: E8
LifeTime and improving European healthcare through cell-based interceptive medicine

The LifeTime initiative is an ambitious, multidisciplinary programme that aims to improve healthcare by tracking individual human cells during disease processes and responses to treatment in order to develop and implement cell-based interceptive medicine in Europe.

Nikolaus Rajewsky
Geneviève Almouzni
Frauke Zipp
Reviews07 Sept 2020
Nature

Volume: 587, P: 377-386
Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study

Frauke Beyer
Rui Zhang
A. Veronica Witte
ResearchOpen Access25 Oct 2020
International Journal of Obesity

Volume: 45, P: 491-501
A longitudinal resource for population neuroscience of school-age children and adolescents in China

Xue-Ru Fan
Yin-Shan Wang
Xi-Nian Zuo
ResearchOpen Access21 Aug 2023
Scientific Data

Volume: 10, P: 1-24

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