Nature Search

Development of an allosteric adhesion GPCR nanobody with therapeutic potential

A nanobody was identified that targets the N-terminal fragment of the adhesion G-protein-coupled receptor ADGRG2, allosterically enhances activation by the natural agonist dehydroepiandrosterone and restores signaling in mutant receptors.

Yuan Zheng
Dan Jiang
Shiqing Feng
Research15 May 2025
Nature Chemical Biology

P: 1-12
Circular RNA-mediated inverse prime editing in human cells

Prime editors are restricted to performing precise edits downstream of cleavage sites. Here, authors develop helicase-assisted circular RNA-mediated inverse PEs (ciPEs) to increase editing efficiencies at previously challenging genomic sites, expanding the scope of precise genome editing.

Ronghong Liang
Shan Wang
Caixia Gao
ResearchOpen Access31 May 2025
Nature Communications

Volume: 16, P: 1-11
An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG) is driven by H3K27M oncohistones, but the exact related mechanisms are poorly understood. Here, the authors identify an H3.3K27M oncohistone-driven CREB5/ID1 axis that promotes transcriptional changes and progression in DIPG, which could represent a potential therapeutic target.

Wei Zhou
Cheng Xu
Qiaoran Xi
ResearchOpen Access17 Apr 2025
Nature Communications

Volume: 16, P: 1-22
Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface

Bone-tendon interface repair is a challenge due to the transition between tissues. Here the authors report on magnetic Janus hydrogel microrobots loaded with dual bioactive ions for controlling cell phenotype and structure to promote healing of the bone-tendon interface in rotator cuff tear reconstruction surgery.

Zichuan Ding
Yongrui Cai
Zeyu Luo
ResearchOpen Access04 Mar 2025
Nature Communications

Volume: 16, P: 1-19
Direct recycling of spent cathode material at ambient conditions via spontaneous lithiation

Direct recycling can facilitate the sustainable management of end-of-life spent cathodes, but is hindered by the harsh operation conditions required. An spontaneous lithiation strategy enables direct recycling of spent cathode material at ambient conditions, with clear economic and environmental benefits.

Junxiong Wang
Haocheng Ji
Hui-Ming Cheng
Research20 Aug 2024
Nature Sustainability

Volume: 7, P: 1283-1293
Generative learning assisted state-of-health estimation for sustainable battery recycling with random retirement conditions

Data scarcity and heterogeneity impede the estimation of retired battery capacity. Here, Tao et al. propose a generative learning method that extends measured data space, potentially reducing curation time, cost and facilitating their sustainable reuse and recycling.

Shengyu Tao
Ruifei Ma
Guangmin Zhou
ResearchOpen Access23 Nov 2024
Nature Communications

Volume: 15, P: 1-14
Urea synthesis via electrocatalytic oxidative coupling of CO with NH₃ on Pt

Electrocatalytic urea formation most commonly involves the co-reduction of NO_x species with CO₂. This limits overall energy efficiency as commodity-scale NO_x is produced from N₂ via NH₃. The swings in nitrogen oxidation state can be minimized through direct oxidative electrocatalytic reaction of CO and NH₃ to urea, as shown in this study.

Haocheng Xiong
Peiping Yu
Qi Lu
Research05 Jun 2024
Nature Catalysis

Volume: 7, P: 785-795
The “Podcast” ECoG dataset for modeling neural activity during natural language comprehension

Zaid Zada
Samuel A. Nastase
Uri Hasson
ResearchOpen Access03 Jul 2025
Scientific Data

Volume: 12, P: 1-9
Subtractive transformation of cathode materials in spent Li-ion batteries to a low-cobalt 5 V-class cathode material

Direct recycling or upcycling is promising for sustainable battery resource management. Here, the authors report a subtractive transformation strategy for upcycling spent cathode materials to high-performance 5 V-class cathodes, reducing reliance on rare elements for the sustainable Li-ion battery industry.

Jun Ma
Junxiong Wang
Guangmin Zhou
ResearchOpen Access05 Feb 2024
Nature Communications

Volume: 15, P: 1-10
Concerning the stability of seawater electrolysis: a corrosion mechanism study of halide on Ni-based anode

It is known that chloride anions cause severe anode corrosion during seawater electrolysis. Here we found that bromide in seawater is even more harmful to Ni-based anodes, causing the spalling of the catalyst layer and the formation of shallow-wide pits on the substrate, leading to performance degradation.

Sixie Zhang
Yunan Wang
Zhiyi Lu
ResearchOpen Access10 Aug 2023
Nature Communications

Volume: 14, P: 1-10
CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis

Ziyun Li
Jia Jiang
Jinzhong Zhao
ResearchOpen Access24 Feb 2025
Bone Research

Volume: 13, P: 1-16
Collaborative and privacy-preserving retired battery sorting for profitable direct recycling via federated machine learning

Unsorted retired batteries pose recycling challenges due to diverse cathodes. Here, the authors propose a privacy-preserving machine learning system that enables accurate sorting with minimal data, important for a sustainable battery recycling industry.

Shengyu Tao
Haizhou Liu
Hongbin Sun
ResearchOpen Access05 Dec 2023
Nature Communications

Volume: 14, P: 1-14
An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness

Activated Notch signalling promotes cancer metastasis and stemness. Here the authors show that Notch1 activates transcription of DNA replication factor RCF4 and that RCF4 binds and stabilises Notch1 intracellular ___domain (NICD1) to promote cancer metastasis.

Lei Liu
Tianyu Tao
Han Tian
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-16
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Bone mineral density (BMD) is associated with fracture risk and many genetic loci with small effect sizes have been discovered by genome-wide association studies (GWAS). Here, the authors discover a large-effect rare loss-of-function genetic variant for BMD in the MEPE gene in the Norwegian HUNT study which replicates in the UK Biobank.

Ida Surakka
Lars G. Fritsche
Cristen J. Willer
ResearchOpen Access23 Oct 2020
Nature Communications

Volume: 11, P: 1-8
Two stage multiobjective topology optimization method via SwinUnet with enhanced generalization

Cheng Xiang
Airong Chen
Haocheng Chang
ResearchOpen Access18 Mar 2025
Scientific Reports

Volume: 15, P: 1-21
Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex

Ketamine is a short-acting analgesic that also has anti-depressant effects. Here the authors show in rat models of chronic pain that low-dose ketamine can induce an anti-aversive state that persists after the initial short term analgesia has ended.

Haocheng Zhou
Qiaosheng Zhang
Jing Wang
ResearchOpen Access14 Sept 2018
Nature Communications

Volume: 9, P: 1-13
Multi-layer regional railway network and equitable economic development of megaregions

Chengcheng Yu
Wentao Dong
Quan Yuan
ResearchOpen Access19 Jan 2025
npj Sustainable Mobility and Transport

Volume: 2, P: 1-12
A STING-activating nanovaccine for cancer immunotherapy

STING-activating nanoparticle vaccines achieve robust activation of tumour-specific T cells for cancer immunotherapy.

Min Luo
Hua Wang
Jinming Gao
Research24 Apr 2017
Nature Nanotechnology

Volume: 12, P: 648-654
Author Correction: Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Junjie Lin
Xin Zhang
Renqing Zhao
Amendments and CorrectionsOpen Access19 Aug 2024
Scientific Reports

Volume: 14, P: 1
Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Junjie Lin
Xin Zhang
Renqing Zhao
ResearchOpen Access09 May 2024
Scientific Reports

Volume: 14, P: 1-14
Spatial-temporal characteristics and the epidemiology of haemorrhagic fever with renal syndrome from 2007 to 2016 in Zhejiang Province, China

Haocheng Wu
XinYi Wang
Junfen Lin
ResearchOpen Access06 Jul 2018
Scientific Reports

Volume: 8, P: 1-14
Local field potential decoding of the onset and intensity of acute pain in rats

Qiaosheng Zhang
Zhengdong Xiao
Jing Wang
ResearchOpen Access29 May 2018
Scientific Reports

Volume: 8, P: 1-11
Laminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells

Congzhen Qiao
Shengdi Li
Jifeng Zhang
ResearchOpen Access05 Feb 2018
Scientific Reports

Volume: 8, P: 1-9

Search

Development of an allosteric adhesion GPCR nanobody with therapeutic potential

Circular RNA-mediated inverse prime editing in human cells

An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma

Janus hydrogel microrobots with bioactive ions for the regeneration of tendon-bone interface

Direct recycling of spent cathode material at ambient conditions via spontaneous lithiation

Generative learning assisted state-of-health estimation for sustainable battery recycling with random retirement conditions

Urea synthesis via electrocatalytic oxidative coupling of CO with NH₃ on Pt

The “Podcast” ECoG dataset for modeling neural activity during natural language comprehension

Subtractive transformation of cathode materials in spent Li-ion batteries to a low-cobalt 5 V-class cathode material

Concerning the stability of seawater electrolysis: a corrosion mechanism study of halide on Ni-based anode

CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis

Collaborative and privacy-preserving retired battery sorting for profitable direct recycling via federated machine learning

An RFC4/Notch1 signaling feedback loop promotes NSCLC metastasis and stemness

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Two stage multiobjective topology optimization method via SwinUnet with enhanced generalization

Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex

Multi-layer regional railway network and equitable economic development of megaregions

A STING-activating nanovaccine for cancer immunotherapy

Author Correction: Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Spatial-temporal characteristics and the epidemiology of haemorrhagic fever with renal syndrome from 2007 to 2016 in Zhejiang Province, China

Local field potential decoding of the onset and intensity of acute pain in rats

Laminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells

Search

Quick links

Search

Filter By:

Search

Quick links