Nature Search

Tailored ozone activation on geometrical-site-dependent cobalt with selective coordination

Geometrical-site-dependent catalytic ozone activation is demonstrated on the Co²⁺_Td and Co³⁺_Oh sites in spinel oxides, where the spin-polarized Co²⁺_Td outperforms Co³⁺_Oh site in •OH generation, achieving a 17.6-fold increase in turnover frequency.

Shenning Liu
Yuxian Wang
Shaobin Wang
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche

The histone methyltransferase ASH1L has been linked to tumorigenesis, mainly in leukemia. Here, authors report that ASH1L cooperates with HIF-1α to induce a pro-metastatic transcriptome in prostate cancer cells, and promotes conversion of monocytes to lipid-associated tumor-associated macrophages in the bone metastatic niche.

Chenling Meng
Kevin Lin
Di Zhao
ResearchOpen Access20 May 2025
Nature Communications

Volume: 16, P: 1-23
Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 2011–2021, revealing increased genetic diversity and dominance of highly virulent ST208.

Qixia Luo
Mengru Chang
Yonghong Xiao
ResearchOpen Access14 Apr 2025
Nature Communications

Volume: 16, P: 1-17
The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

Infection with SARS-CoV-2 causes interstitial pneumonia and viral replication in the lungs of transgenic mice that express a human version of ACE2, confirming the pathogenicity of the virus in this model.

Linlin Bao
Wei Deng
Chuan Qin
Research07 May 2020
Nature

Volume: 583, P: 830-833
Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice

The molecular network controlling seed size remains elusive. Using genetic and functional analyses, researchers found that the transcription factor OsGRF4 (GS2) forms a module with its regulator OsmiR396 and coactivator GIFs to regulate grain size in rice.

Penggen Duan
Shen Ni
Yunhai Li
Research21 Dec 2015
Nature Plants

Volume: 2, P: 1-5
CRISPR–Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames

The authors show that the lncRNA-derived microprotein SMIMP, which is shown to promote tumor formation, regulates cohesin core subunit binding to cis-regulatory elements and alters the expression of tumor-suppressive cell cycle regulators.

Caishang Zheng
Yanjun Wei
Yiwen Chen
ResearchOpen Access06 Nov 2023
Nature Structural & Molecular Biology

Volume: 30, P: 1878-1892
Correction: Corrigendum: Regulation of OsGRF4 by OsmiR396 controls grain size and yield in rice

Penggen Duan
Shen Ni
Yunhai Li
Amendments and Corrections05 Jan 2016
Nature Plants

Volume: 2, P: 1
A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

A recombinant vaccine that targets the receptor-binding ___domain of the spike protein of SARS-CoV-2 induces a potent antibody response in immunized mice, rabbits and non-human primates, and protects primates from infection with the virus.

Jingyun Yang
Wei Wang
Xiawei Wei
Research29 Jul 2020
Nature

Volume: 586, P: 572-577
A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Leukemia inhibitory factor receptor (LIFR) is frequently downregulated in liver cancer. Here the authors show that loss of LIFR promotes liver tumorigenesis and confers resistance to drug-induced ferroptosis through NF-κB-mediated upregulation of iron-sequestering cytokine LCN2.

Fan Yao
Yalan Deng
Li Ma
ResearchOpen Access17 Dec 2021
Nature Communications

Volume: 12, P: 1-17
The subcommissural organ regulates brain development via secreted peptides

The subcommissural organ (SCO) is a gland in the brain, and relatively little is known about its function. Zhang et al. genetically ablated SCO cells and observed severe hydrocephalus and neuronal defects. The reintroduction of SCO-derived peptides into SCO-ablated brain substantially rescued developmental defects.

Tingting Zhang
Daosheng Ai
Woo-ping Ge
Research13 May 2024
Nature Neuroscience

Volume: 27, P: 1103-1115
Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance

The molecular mechanisms underlying cancer cell radioresistance need to be elucidated. In this study, the authors show that the microRNA biogenesis factor DGCR8 is stabilized by USP51 and ATM upon irradiation and by consequence it promotes the repair of DNA double-strand breaks and radioresistance by recruiting RNF168 to sites of damage.

Qinglei Hang
Liyong Zeng
Li Ma
ResearchOpen Access29 Jun 2021
Nature Communications

Volume: 12, P: 1-18
Copy number variation at the GL7 locus contributes to grain size diversity in rice

Jiayang Li, Xudong Zhu, Qian Qian and colleagues report cloning of the Grain Length on Chromosome 7 (GL7) locus in rice and identify a copy number variant that increases grain length and improves grain quality. They demonstrate how interactions with other grain length–related genes may be used to improve breeding.

Yuexing Wang
Guosheng Xiong
Qian Qian
Research06 Jul 2015
Nature Genetics

Volume: 47, P: 944-948
Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

Jingyun Yang
Wei Wang
Xiawei Wei
Amendments and Corrections19 Jan 2021
Nature

Volume: 590, P: E23
Genomic basis of the giga-chromosomes and giga-genome of tree peony Paeonia ostii

Tree peony (Paeonia ostii) has the largest chromosome of any sequenced plants to date. Here, the authors assemble its genome and reveal the association of a list of candidate genes with fatty acid biosynthesis and the possible contribution of transposon and histone expansion to maintain the giga-chromosomes.

Junhui Yuan
Sanjie Jiang
Yonghong Hu
ResearchOpen Access28 Nov 2022
Nature Communications

Volume: 13, P: 1-16
SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells

The cystine transporter SLC7A11 protects cancer cells from oxidative stress by supporting glutathione synthesis. Here, the authors show that the expression level of SLC7A11 leads to different outcomes depending on context, so high expression promotes primary tumour growth but promotes disulfide stress under oxidative stress conditions and impairs metastasis.

Yuelong Yan
Hongqi Teng
Boyi Gan
ResearchOpen Access21 Jun 2023
Nature Communications

Volume: 14, P: 1-15
Distribution of two CD4⁺FOXP3⁺ T cell subpopulations reflects disease phenotypes and prognosis in COPD

Jia Hou
Jiale Zhao
Juan Chen
ResearchOpen Access22 May 2025
Scientific Reports

Volume: 15, P: 1-9
Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity

Huang et al. show that, in response to chemotherapy, PTEN directly interacts with NLRP3 in myeloid cells to enhance inflammasome activation and antitumour immune responses.

Yi Huang
Huanyu Wang
Rongbin Zhou
Research04 May 2020
Nature Cell Biology

Volume: 22, P: 716-727
Radioprotective effects and mechanism of HL-003 on radiation-induced salivary gland damage in mice

Jingming Ren
Rong Huang
Chenlu Liu
ResearchOpen Access19 May 2022
Scientific Reports

Volume: 12, P: 1-10
A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China

Authors carry out a genomic analysis of carbapenem-resistant Klebsiella pneumoniae bloodstream isolates, noting subclonal expansion, associated with the emergence of a hypervirulent subpopulation.

Kai Zhou
Chun-Xu Xue
Yonghong Xiao
ResearchOpen Access28 Apr 2023
Nature Communications

Volume: 14, P: 1-14
An interpretable deep learning workflow for discovering subvisual abnormalities in CT scans of COVID-19 inpatients and survivors

Respiratory complications after a COVID infection are a growing concern, but follow-up chest CT scans of COVID-19 survivors hardly present any recognizable lesions. A deep learning-based method was developed that calculates a scan-specific optimal window and removes irrelevant tissues such as airways and blood vessels from images with segmentation models, so that subvisual abnormalities in lung scans become visible.

Longxi Zhou
Xianglin Meng
Xin Gao
ResearchOpen Access23 May 2022
Nature Machine Intelligence

Volume: 4, P: 494-503
The effect of selenium biological enhancement on cucumber growth and powdery mildew control under greenhouse conditions

Xiaodi Xu
Zhangbo Chen
Kai Pan
ResearchOpen Access26 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss

Lin Qiu
Hongwei Li
Xiaoyang Wang
ResearchOpen Access20 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
Convolution neural network with batch normalization and inception-residual modules for Android malware classification

TianYue Liu
HongQi Zhang
YuHua Yao
ResearchOpen Access17 Aug 2022
Scientific Reports

Volume: 12, P: 1-17
Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference–based bone anabolic strategy

Chao Liang
Baosheng Guo
Ge Zhang
Research09 Feb 2015
Nature Medicine

Volume: 21, P: 288-294
Determining levels of linguistic deficit by applying cluster analysis to the aphasia quotient of Western Aphasia Battery in post-stroke aphasia

Zhijie Yan
Dongshuai Wei
Jie Jia
ResearchOpen Access06 Sept 2022
Scientific Reports

Volume: 12, P: 1-5
Ventilatory pressure parameters impact the association between acute gastrointestinal injury and all-cause mortality in mechanically ventilated patients

Shao Ziqiang
Li Jiale
Hu Bangchuan
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
Strategic targeting of miR-183 and β-catenin to enhance BMSC stemness in age-related osteoporosis therapy

Nizhou Jiang
Jian Jiang
Hong Wang
ResearchOpen Access14 Sept 2024
Scientific Reports

Volume: 14, P: 1-14
Molecular evolution of Wcor15 gene enhanced our understanding of the origin of A, B and D genomes in Triticum aestivum

Fangfang Liu
Hongqi Si
Chuanxi Ma
ResearchOpen Access16 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
Genome-wide analysis of fatty acid desaturase genes in rice (Oryza sativa L.)

Zhiguo E
Chen Chen
Hongqi Chen
ResearchOpen Access19 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Gap-free genome assembly of Salangid icefish Neosalanx taihuensis

Yanfeng Zhou
Xizhao Zhang
Chunhai Chen
ResearchOpen Access04 Nov 2023
Scientific Data

Volume: 10, P: 1-11
Asymmetric impact of climatic parameters on hemorrhagic fever with renal syndrome in Shandong using a nonlinear autoregressive distributed lag model

Yongbin Wang
Ziyue Liang
Fei Lin
ResearchOpen Access28 Apr 2024
Scientific Reports

Volume: 14, P: 1-12
Ubiquitination of Rheb governs growth factor-induced mTORC1 activation

Lu Deng
Lei Chen
Ping Wang
ResearchOpen Access04 Dec 2018
Cell Research

Volume: 29, P: 136-150
TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer

Nengquan Sheng
Li Yan
Zhigang Wang
ResearchOpen Access14 Mar 2018
Cell Death & Disease

Volume: 9, P: 1-14
MicroRNA-181a–2–3p shuttled by mesenchymal stem cell-secreted extracellular vesicles inhibits oxidative stress in Parkinson’s disease by inhibiting EGR1 and NOX4

Jianjun Ma
Xiaoxue Shi
Xue Li
ResearchOpen Access24 Jan 2022
Cell Death Discovery

Volume: 8, P: 1-14
Three TaFAR genes function in the biosynthesis of primary alcohols and the response to abiotic stresses in Triticum aestivum

Meiling Wang
Yong Wang
Zhonghua Wang
ResearchOpen Access26 Apr 2016
Scientific Reports

Volume: 6, P: 1-14
Analysis of the role of Purα in the pathogenesis of Alzheimer's disease based on RNA-seq and ChIP-seq

Xiaoguang Shi
Shuanglai Ren
Jianqi Cui
ResearchOpen Access09 Jun 2021
Scientific Reports

Volume: 11, P: 1-12
High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression

Jing Wang
Xuefang Shen
Changhong Miao
ResearchOpen Access21 May 2020
Cell Death & Disease

Volume: 11, P: 1-14
Identification of Biomarkers Based on Differentially Expressed Genes in Papillary Thyroid Carcinoma

Jun Han
Meijun Chen
Hong Qiao
ResearchOpen Access02 Jul 2018
Scientific Reports

Volume: 8, P: 1-11
Gap-free genome assembly of anadromous Coilia nasus

Fengjiao Ma
Yinping Wang
Kai Liu
ResearchOpen Access06 Jun 2023
Scientific Data

Volume: 10, P: 1-10
Author Correction: Determining levels of linguistic deficit by applying cluster analysis to the aphasia quotient of Western Aphasia Battery in post-stroke aphasia

Zhijie Yan
Dongshuai Wei
Jie Jia
Amendments and CorrectionsOpen Access01 Dec 2022
Scientific Reports

Volume: 12, P: 1
A multi-centre randomised trial comparing ultrasound vs mammography for screening breast cancer in high-risk Chinese women

S Shen
Y Zhou
Q Sun
ResearchOpen Access10 Feb 2015
British Journal of Cancer

Volume: 112, P: 998-1004

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