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Author Correction: MYC phase separation selectively modulates the transcriptome

Junjiao Yang
Chan-I Chung
Xiaokun Shu
Amendments and Corrections12 Jun 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1808
MYC phase separation selectively modulates the transcriptome

Oncoprotein transcription factor MYC undergoes phase separation, forming transcriptionally active condensates. The chemogenetic tool SPARK-ON reveals that MYC phase separation selectively modulates the transcriptome and promotes cell proliferation.

Junjiao Yang
Chan-I Chung
Xiaokun Shu
Research29 May 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1567-1579
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

Neuroblastoma (NB) is often driven by MYCN amplification. Here, the authors show that the most frequent genetic lesion, gain of 17q21-ter in NB leads to overexpression of ALYREF, which forms a complex with MYCN, regulating MYCN stability via the deubiquitinating enzyme, USP3.

Zsuzsanna Nagy
Janith A. Seneviratne
Glenn M. Marshall
ResearchOpen Access25 Mar 2021
Nature Communications

Volume: 12, P: 1-20

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