Innate lymphoid cells (ILC) are instrumental to immediate, local response to pathogens. Here the authors use parabiosis and multiplex 3D imaging to identify a mouse type 3 ILC population that resides in the intravascular space of lung, produces CCL4 for neutrophil recruitment, and protects from Pseudomonas aeruginosa infection in mice.
- Simon Shirley
- Hiroshi Ichise
- Yuefeng Huang