A hybrid surface electrode array was developed, which exhibits superior signal-to-noise ratio (SNR) and outstanding conformality with the cortex surface. It was used to detect the brain signals in awake, free-moving rat models with high-throughput spatiotemporal resolution. In addition, the pilocarpine-induced epileptic discharges and behavior were considerably suppressed upon the usage of this electrode-array system. These findings pave the way for the integration of graphene into bio-medical device platforms, and their use in cranial neuropathy treatment.
- Jeongsik Lim
- Sangwon Lee
- Jong-Hyun Ahn