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Stabilizing lithium-metal anodes is challenging due to their high reactivity with electrolytes. This work presents a dual-passivation polymer coating that enhances solid–electrolyte interphase stability, improving cycling performance and increasing capacity retention over extended cycles.

Zhang et al. show that the activation of RIPK1 is suppressed by acetylhypusination in a spermidine-dependent manner. Disruption of this axis contributes to RIPK1-mediated vascular pathology to promote insulin resistance and diabetic kidney pathology.

Solid polymer electrolytes suffer from limited ionic conductivity and poor interfacial stability for lithium batteries. Here, authors propose a fluorinated ether diluent to reduce the dipole-dipole interaction of ionic solvate with the polymer matrix and induce the formation of aggregates.

Qifa Zhang and colleagues report the map-based cloning of the quantitative trait locus GS5, which regulates grain size and yield in rice. GS5 encodes a putative serine carboxypeptidase and increased expression is associated with larger grain.

Artificial intelligence-based detection of gastric cancer at different stages from noncontrast computed tomography is suggested to be feasible in a retrospective analysis of large and diverse cohorts, including real-world populations in opportunistic and targeted screening scenarios.

The H9N2 avian influenza viruses (AIVs) remain dominant in live poultry markets in China, and H9N2 AIVs with HA-Q226L, PB2-V/K627 and NP-N52 mutations can be transmitted between guinea pigs and between ferrets via direct contact and respiratory droplet.

DeepRETStroke is a deep learning system using retinal photographs to detect silent brain infarction and predict future stroke events.

High-voltage positive electrodes in sulfide all-solid-state lithium batteries face challenges due to the low oxidation stability of sulfide electrolytes. Here, authors propose a Li₂ZrF₆ coating on LiCoO₂ to suppress interfacial reactions and enhance the long-term battery cycling performance.

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

Protein citrullination regulates the physiological function of proteins and is linked to various autoimmune disorders. Here, the authors report on the allosteric targeting of PAD1-4 leading to broad inhibition of protein citrullination in neutrophils.

Absorption and accumulation of atmospheric microplastics by plant leaves occurs widely in the environment.

TPP endows TPP₃Cu₂Br₂ with both excellent water resistance and sensitive temperature-dependent luminescence lifetime, achieving a S_r up to 12.82% K⁻¹.

The authors demonstrated that RNA helicase RH24 responds to temperature fluctuation and coordinately controls the accumulation of RH24-ILR3 condensate with iron regulator BTS to fine-tune iron uptake, thus alleviating iron overload-caused damage in chilling stress response in Arabidopsis.

A vanadium-based lithium-rich disordered rock salt oxide is shown to work as a low-potential anode with rapid intercalation kinetics for lithium-ion batteries.

High-throughput and reversible characterization of microscale light-emitting diode wafers can be performed using a flexible probe head containing arrays of elastomer microposts, which reduce surface defects and probe wear.

Electrochemically mediated CO₂ capture is a developing alternative to conventional temperature and pressure-swing processes but faces challenges of stability and selectivity. Here, authors develop redox-tunable Brønsted acids to enable electrochemical CO₂ capture in nonvolatile organic solvents.

Solution-based methods exist to upcycle waste polyolefins, although these resort to the use of co-reactants and require non-negligible energy inputs. Here the authors show how a solar thermal catalytic system based on copper particles encapsulated within a 2D Si material can strongly alleviate such issues.

Li-In alloys are widely used as reference materials in the research field of solid-state lithium-based batteries. Here, the authors report and discuss the instability of Li-In electrodes towards sulfide solid electrolytes in all-solid-state batteries.

The mechanical stability of catalytic electrodes is crucial for anion exchange membrane water electrolysis. Here, the authors report a corrosion strategy to construct an electrode with high mechanical stability by anchoring a blade-shaped catalytic layer onto a dense interlayer.

Lithium battery performance hinges significantly on the solvation structure of the electrolyte and the resulting interphase. Here the authors introduce a fluorinated ether with minimal lithium-ion coordination and enhanced electrochemical stability, thus improving both cyclability and calendar life.

In a multicenter randomized phase 3 trial, stapokibart, a humanized monoclonal antibody that targets IL-4R alpha, significantly improved daily nasal and ocular symptom scores during the pollen phase in patients with moderate-to-severe seasonal allergic rhinitis.

In Li-ion batteries, single crystalline cobalt-free lithium transition metal oxides are less understood than their polycrystalline counterparts. Here, authors show that the absence of cobalt in single crystalline oxides results in structural degradation that ultimately degrades battery performance.

The understanding of the reemergence of pressure induced superconductivity in alkali-metal intercalated FeSe is hampered by sample complexities. Here, Sun et al. report the electronic properties of (Li_1–xFe _x )OHFe_1–ySe single crystal not only in the reemerged superconducting state but also in the normal state.

Improving oxygen evolution in acidic water electrolysis is vital for advancing clean hydrogen production. Here, the authors report that doping ruthenium oxide with selenium enhances efficiency and durability by tuning orbital band gaps, improving electron flow, and stabilizing oxygen vacancies.

Here, the authors introduce a single-cell Hi-C method to study mammalian sperm, suggesting chromatin compartments but absent topological domains (TADs) or loops. It clarifies the unique 3D nuclear architecture of sperm and offers a foundation for investigating structural anomalies associated with male infertility.

In a quantum simulation of a (2+1)D lattice gauge theory using a superconducting quantum processor, the dynamics of strings reveal the transition from deconfined to confined excitations as the effective electric field is increased.

A novel covalent inhibitor, ISM3312, targets the main protease of multiple human coronaviruses, including drug-resistant strains, and shows broad antiviral activity. It offers a promising therapeutic strategy against current and future coronavirus threats.

Here they identify a selective PRC1.1 inhibitor, iBP, that treats bone loss by improving osteoblast function. iBP releases repression of Wnt/β-catenin signaling, enhancing bone formation and repair in aging, trauma, and disease models.

Drought, fires, and human activities have reversed the accumulation of live biomass carbon in the Northern Hemisphere, with total biomass shifting from a positive to a negative trend around 2016.

Through multimodal analyses of human cardiac tissues across different ages, Fan, Zheng, Zhan, Xu, Liu and colleagues reveal that RNA-binding protein ARID5A drives inflammaging by stabilizing the MAVS mRNA and activating the NF-κB–TBK1 pathway, and show that inactivating myocardial ARID5A attenuates cardiac senescence and functional decline.

Immune checkpoint inhibitors have shown some activity in patients with adrenocortical carcinoma (ACC), a rare aggressive malignancy with limited treatment options. Here the authors report the results of a phase 2 trial of camrelizumab (anti-PD1) plus apatinib (VEGFR inhibitor) for previously treated ACC.

Hot carrier transport in organic systems has remained elusive due to rapid energy relaxation and limited transport properties. Here highly mobile hot carriers and their relaxation dynamics are reported in a crystalline two-dimensional conjugated coordination polymer, revealing two distinct transport regimes.

Low-temperature operation remains challenging for batteries. Here, the authors report an electrolyte solvation structure design strategy to break solvation dominance of ethylene carbonate to facilitate the desolvation process that improves the low-temperature performance of lithium-ion batteries even below −100 °C.

Lithium metal is considered an ideal anode for high-energy rechargeable lithium batteries, but understanding its nucleation and growth at the nanoscale remains challenging. Using cryogenic transmission electron microscopy and simulations, a structural and morphological evolution scenario for Li deposits is proposed.

Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their molecular details and provides tools for further studies in pea genetics, functional genomics and crop improvement.

A-kinase anchoring protein 1 (AKAP1) promotes the assembly of signalosomes on the mitochondrial outer membrane and act as a central hub for mitochondrial signalling. Here, the authors show that AKAP1 protects against MASLD progression by inhibiting mitochondrial GPAT1 activity and subsequent lysophosphatidic acid production.

All-optical image processing using metasurfaces is advancing due to its high speed, integrability, and low energy consumption, yet background noise and clutter hinder the progress. In this work, a real-time optical image processor is introduced, using a metal-dielectric-metal film to perform spatial band-pass filtering in momentum space enabling high-resolution edge detection and real-time dynamic denoising.

The authors developed a highly conductive and dielectric composite solid-state electrolyte by coupling BaTiO₃ and Li_0.33La_0.56TiO_3–x nanowires with a side-by-side heterojunction structure in a polyvinylidene difluoride matrix, which simultaneously promotes the dissociation of lithium salts to produce more movable Li ions and efficiently transports the generated movable Li ions.

This study reports the horizontal gene transfer of CSP genes from bacteria to Triticeae, promoting the adaptation and spread of wheat through enhanced drought tolerance and photosynthetic efficiency.

Polysubstituted arenes are ubiquitous structural cores in natural products and drugs but their synthesis through programmable arene modification remains a challenge. Now, a palladium- and norbornene-catalysed Catellani-type reaction of aryl ketones, through successive acylation and deacylation, allows the synthesis of polysubstituted arenes.