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Nature Cell Biology (3)
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Showing 1–5 of 5 results

Advanced filters: Author: Linjia Jiang Clear advanced filters

Selective translational control by PABPC1 phase separation regulates blast crisis and therapy resistance in chronic myeloid leukaemia

Sun et al. identify a role for PABPC1 in selectively regulating the translation of leukaemogenic mRNAs to promote blast crisis transition, which may be targeted to overcome resistance to TKI treatment in chronic myeloid leukaemia.

Chenguang Sun
Xi Xu
Yanni Ma
Research18 Mar 2025
Nature Cell Biology

Volume: 27, P: 683-695
PD-1 signalling defines and protects leukaemic stem cells from T cell receptor-induced cell death in T cell acute lymphoblastic leukaemia

Xu, Zhang, Xuan et al. show that PD-1 signalling defines a population of leukaemia stem cells with features of quiescence, drug resistance and protection against cell death, ablation of which suppresses disease progression of mouse and human T-ALL.

Xi Xu
Wenwen Zhang
Meng Zhao
Research09 Jan 2023
Nature Cell Biology

Volume: 25, P: 170-182
SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming

Xu, Yu, Zhang, Ma, He and colleagues show that SHP-1 inhibition causes increased glycolysis and oxidative phosphorylation through PFKP in leukaemia stem cells, thereby promoting immunosurveillance and chemosensitivity in acute myeloid leukaemia.

Xi Xu
Yanhui Yu
Linjia Jiang
Research06 Feb 2024
Nature Cell Biology

Volume: 26, P: 464-477
SERS monitoring of photoinduced-enhanced oxidative stress amplifier on Au@carbon dots for tumor catalytic therapy

Core-shell structured Au@carbon dots are fabricated to present a photoinduced-enhanced oxidative stress amplification, which can be efficiently used for tumor catalytic therapy by surface-enhanced Raman scattering technique.

Linjia Li
Jin Yang
Wei Song
ResearchOpen Access30 Sept 2022
Light: Science & Applications

Volume: 11, P: 1-11
YIPF2 is a novel Rab-GDF that enhances HCC malignant phenotypes by facilitating CD147 endocytic recycle

Shanshan Qi
Linjia Su
Sihe Zhang
ResearchOpen Access12 Jun 2019
Cell Death & Disease

Volume: 10, P: 1-16