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Showing 1–4 of 4 results
Advanced filters: Author: Linzixuan Zhang Clear advanced filters

  • Intradermal microneedles for the co-delivery of mRNA and near-infrared fluorescent microparticles are used in combination with deep learning-based image analysis for the simultaneous administration of therapeutics and registry of patient information records into the skin.

    • Jooli Han
    • Maria Kanelli
    • Ana Jaklenec
    ResearchOpen Access
    Nature Materials
    Volume: 24, P: 794-803

  • This study reports the preparation of degradable poly(β-amino ester) microparticles as a promising replacement for nondegradable microplastics in cleansing products and food fortification, demonstrating effective cleansing, toxic element removal and robust nutrient protection with efficient release.

    • Linzixuan Zhang
    • Ruiqing Xiao
    • Ana Jaklenec
    ResearchOpen Access
    Nature Chemical Engineering
    Volume: 2, P: 77-89

  • CRISPR–Cas9 technology is a powerful tool for immune cell engineering. Ex vivo editing has progressed to clinical trials, but in vivo applications are still limited owing to delivery challenges. This Review summarizes these challenges as well as strategies and progress in delivering CRISPR–Cas9 to immune and non-immune cells.

    • Shahad K. Alsaiari
    • Behnaz Eshaghi
    • Ana Jaklenec
    Reviews
    Nature Reviews Materials
    Volume: 10, P: 44-61