Nature Search

A noncanonical role of SAT1 enables anchorage independence and peritoneal metastasis in ovarian cancer

SAT1 is a rate-limiting enzyme in polyamine catabolism. Here, authors discover a non-canonical function of SAT1 regulating H3K27ac marks within genes required for mitosis regulation and chromosome segregation, enabling anchorage-independent cell survival and peritoneal metastasis of ovarian cancer cells.

Cuimiao Zheng
Gang Niu
Chaoyun Pan
ResearchOpen Access03 Apr 2025
Nature Communications

Volume: 16, P: 1-20
Selective translational control by PABPC1 phase separation regulates blast crisis and therapy resistance in chronic myeloid leukaemia

Sun et al. identify a role for PABPC1 in selectively regulating the translation of leukaemogenic mRNAs to promote blast crisis transition, which may be targeted to overcome resistance to TKI treatment in chronic myeloid leukaemia.

Chenguang Sun
Xi Xu
Yanni Ma
Research18 Mar 2025
Nature Cell Biology

Volume: 27, P: 683-695
METTL3 preferentially enhances non-m⁶A translation of epigenetic factors and promotes tumourigenesis

Wei et al. identify that cytoplasmic METTL3 interacts with PABPC1 to facilitate translation of epigenetic factor mRNAs without m⁶A modification to promote tumour progression, suggesting an m⁶A-independent mechanism for this methyltransferase.

Xueju Wei
Yue Huo
Jia Yu
Research04 Aug 2022
Nature Cell Biology

Volume: 24, P: 1278-1290
Compound heterozygous variants of THG1L result in autosomal recessive cerebellar ataxia

Rui Han
Manman Chu
Xiaoli Zhang
Research05 Sept 2023
Journal of Human Genetics

Volume: 68, P: 843-848
A nomogram based on psoas muscle index predicting long-term cirrhosis incidence in non-cirrhotic patients with HBV-related acute‑on‑chronic liver failure

Jie Bai
Manman Xu
Yongguo Li
ResearchOpen Access02 Dec 2023
Scientific Reports

Volume: 13, P: 1-8
Dynamic coordination engineering of 2D PhenPtCl₂ nanosheets for superior hydrogen evolution

Exploring the dynamic structural evolution of electrocatalysts during electrochemical reactions is imperative. Here, the authors constructed 2D PhenPtCl₂ nanosheets with Phen-Pt-Cl₂ coordination structure which exhibit dynamic coordination evolution during hydrogen evolution reaction and good performance across the full pH range

Gonglei Shao
Changfei Jing
Zhen Zhou
ResearchOpen Access09 Jan 2024
Nature Communications

Volume: 15, P: 1-10
Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity

Hongguo Zhao
Peng Liu
Xinbin Li
ResearchOpen Access24 Jan 2025
Scientific Reports

Volume: 15, P: 1-12
Morphology and transport characterization of solution-processed rubrene thin films on polymer-modified substrates

Xujing Gao
Wentao Liu
Chengshen Zhu
ResearchOpen Access22 Jul 2020
Scientific Reports

Volume: 10, P: 1-8
Association of myosteatosis with short-term outcomes in patients with acute-on-chronic liver failure

Nan Geng
Ming Kong
Zhongping Duan
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-9
Genetic diversity, population structure, and DNA fingerprinting of Ailanthus altissima var. erythrocarpa based on EST-SSR markers

Manman Zhang
Conghui Zheng
Kejiu Du
ResearchOpen Access07 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

Zhenjun Yu
Yu Zhang
Tao Han
ResearchOpen Access19 Jan 2021
Scientific Reports

Volume: 11, P: 1-13
Efficiency and stability enhancement of perovskite solar cells by introducing CsPbI₃ quantum dots as an interface engineering layer

Due to the matching energy level of CsPbI₃ quantum dots and perovskite layer, the efficiency of perovskite solar cells was substantially enhanced from 15.17% to 18.56% by introducing CsPbI₃ quantum dots as interface engineering layer. Moreover, perovskite solar cells with CsPbI₃ QDs maintained 82% of its initial performance for 30 days at over 30% RH without any encapsulation.

Chang Liu
Manman Hu
Chun Cheng
ResearchOpen Access18 Jun 2018
NPG Asia Materials

Volume: 10, P: 552-561
Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis

Chunyu Zhang
Pan Liu
Shuzhong Yao
ResearchOpen Access29 Sept 2021
Cell Death & Disease

Volume: 12, P: 1-13
The synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression

Manman Deng
Jinshui Tan
Bing Xu
ResearchOpen Access29 Oct 2023
Scientific Reports

Volume: 13, P: 1-10
Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy

Yang Deng
Rui Duan
Junrong Zhu
ResearchOpen Access20 Dec 2022
Cell Death & Disease

Volume: 13, P: 1-16
Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer

Yuandong Liao
Jiaming Huang
Shuzhong Yao
ResearchOpen Access12 Feb 2022
Oncogene

Volume: 41, P: 1931-1943
CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability

Chunyu Zhang
Hongye Jiang
Shuzhong Yao
ResearchOpen Access19 Jan 2023
Oncogene

Volume: 42, P: 793-807
High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer

Pan Liu
Chunyu Zhang
Shuzhong Yao
ResearchOpen Access11 Aug 2020
Cell Death & Disease

Volume: 11, P: 1-17
Exogenous avian leukosis virus-induced activation of the ERK/AP1 pathway is required for virus replication and correlates with virus-induced tumorigenesis

Manman Dai
Min Feng
Weisheng Cao
ResearchOpen Access12 Jan 2016
Scientific Reports

Volume: 6, P: 1-15
Oncogenic AURKA-enhanced N⁶-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells

Fei Peng
Jie Xu
Quentin Liu
Research28 Aug 2020
Cell Research

Volume: 31, P: 345-361
Genetic architecture dissection by genome-wide association analysis reveals avian eggshell ultrastructure traits

Zhongyi Duan
Congjiao Sun
Guiyun Xu
ResearchOpen Access26 Jul 2016
Scientific Reports

Volume: 6, P: 1-12
Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2

Bing Xu
Shiyun Wang
Weiguang Wang
ResearchOpen Access18 May 2017
Cell Death & Disease

Volume: 8, P: e2797

Search

A noncanonical role of SAT1 enables anchorage independence and peritoneal metastasis in ovarian cancer

Selective translational control by PABPC1 phase separation regulates blast crisis and therapy resistance in chronic myeloid leukaemia

METTL3 preferentially enhances non-m⁶A translation of epigenetic factors and promotes tumourigenesis

Compound heterozygous variants of THG1L result in autosomal recessive cerebellar ataxia

A nomogram based on psoas muscle index predicting long-term cirrhosis incidence in non-cirrhotic patients with HBV-related acute‑on‑chronic liver failure

Dynamic coordination engineering of 2D PhenPtCl₂ nanosheets for superior hydrogen evolution

Comparative analysis of machine learning approaches for predicting the risk of vaginal laxity

Morphology and transport characterization of solution-processed rubrene thin films on polymer-modified substrates

Association of myosteatosis with short-term outcomes in patients with acute-on-chronic liver failure

Genetic diversity, population structure, and DNA fingerprinting of Ailanthus altissima var. erythrocarpa based on EST-SSR markers

A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators

Efficiency and stability enhancement of perovskite solar cells by introducing CsPbI₃ quantum dots as an interface engineering layer

Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis

The synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression

Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy

Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer

CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability

High expression of PTPRM predicts poor prognosis and promotes tumor growth and lymph node metastasis in cervical cancer

Exogenous avian leukosis virus-induced activation of the ERK/AP1 pathway is required for virus replication and correlates with virus-induced tumorigenesis

Oncogenic AURKA-enhanced N⁶-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells

Genetic architecture dissection by genome-wide association analysis reveals avian eggshell ultrastructure traits

Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2

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