Nature Search

Shared genetic architecture of posttraumatic stress disorder with cardiovascular imaging, risk, and diagnoses

Study shows PTSD predisposition shares distinct genes and genomic regions with several cardiovascular conditions. Here the findings reveal neuronal, immune, and metabolic pathways, and repurposed drug targets that further the understanding of the comorbidity.

Jie Shen
Wander Valentim
Gita A. Pathak
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
Constraints on evolution of Earth's mantle from rare gas systematics

Claude J. Allègre
Thomas Staudacher
Mark Kurz
Research30 Jun 1983
Nature

Volume: 303, P: 762-766
Sex in diploids

MARK KIRKPATRICK
CHERYL D. JENKINS
Research16 Nov 1989
Nature

Volume: 342, P: 232
Anomalous region on Mars: implications for near-surface liquid water

S. H. Zisk
P. J. Mouginis-Mark
Research13 Nov 1980
Nature

Volume: 288, P: 126-129
The risk of Long Covid symptoms: a systematic review and meta-analysis of controlled studies

Estimating the risk of long COVID is challenging because many of its symptoms are associated with other conditions. Here, the authors conduct a systematic review and meta-analysis of studies that estimate long COVID risk while accounting for background symptoms using comparator control populations.

Lauren L. O’Mahoney
Ash Routen
Kamlesh Khunti
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-8
Over-Imitation in the Kalahari Desert and the Origins of Human Cultural Cognition

Mark Nielsen
Keyan Tomaselli
ResearchOpen Access09 Apr 2009
Nature Precedings

P: 1
The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells

Karen B. Avraham
Tama Hasson
Nancy A. Jenkins
Research01 Dec 1995
Nature Genetics

Volume: 11, P: 369-375
Helium isotope disequilibrium and geochronology of glassy submarine basalts

David W. Graham
William J. Jenkins
Rodey Batiza
Research26 Mar 1987
Nature

Volume: 326, P: 384-386
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and show the utility of polygenic risk scores may vary depending on cancer type.

Yan Dora Zhang
Amber N. Hurson
Montserrat Garcia-Closas
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-13
Temperature, phenoxybenzamine and adrenoceptor transformation

GEORGE KUNOS
MARK NICKERSON
Research22 Jan 1976
Nature

Volume: 259, P: 251-252
Defining the extracellular matrix for targeted immunotherapy in adult and pediatric brain cancer

Zoe I. Day
Samuel Roberts-Thomson
Misty R. Jenkins
ResearchOpen Access14 Jun 2025
npj Precision Oncology

Volume: 9, P: 1-14
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Minimum Information about a Neuroscience Investigation (MINI) Electrophysiology

Frank Gibson
Paul Overton
Phillip Lord
ResearchOpen Access25 Mar 2008
Nature Precedings

P: 1
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Here, the authors perform large trans-ancestry fine-mapping analyses identifying large numbers of association signals and putative target genes for colorectal cancer risk, advancing our understanding of the genetic and biological basis of this cancer.

Zhishan Chen
Xingyi Guo
Wei Zheng
ResearchOpen Access26 Apr 2024
Nature Communications

Volume: 15, P: 1-17
Genetic segregation and the maintenance of sexual reproduction

Mark Kirkpatrick
Cheryl D. Jenkins
Research25 May 1989
Nature

Volume: 339, P: 300-301
A comprehensive genetic map of the mouse genome

William F. Dietrich
Joyce Miller
Eric S. Lander
Research14 Mar 1996
Nature

Volume: 380, P: 149-152
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

Harry Pickering
Joanna Schaenman
Charles R. Langelier
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-16
You say diplon, I say deuton

Mark Buchanan
Comments & Opinion01 Oct 2008
Nature Physics

Volume: 4, P: 747
MPSE identifies newborns for whole genome sequencing within 48 h of NICU admission

Bennet Peterson
Edwin F. Juarez
Mark Yandell
ResearchOpen Access12 Jun 2025
npj Genomic Medicine

Volume: 10, P: 1-8
Generalisation of self-thinning of plant populations (reply)

MARK WESTOBY
Research28 Jul 1977
Nature

Volume: 268, P: 373
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower
Michele Harvey
Allan Bradley
Research19 Mar 1992
Nature

Volume: 356, P: 215-221
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide and genetic susceptibility to the disease is poorly understood. Here, the authors combine data from Japanese, African American and European samples and identify a common variant in VTI1Athat increases CRC risk across all populations.

Hansong Wang
Terrilea Burnett
Loïc Le Marchand
Research08 Aug 2014
Nature Communications

Volume: 5, P: 1-7
Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Genetic variants at multiple loci of chr5p15.33 have been associated with susceptibility to numerous cancers. Here the authors show that the association of one of these loci may be explained by a variant, rs36115365, influencing telomerase reverse transcriptase (TERT) expression via ZNF148.

Jun Fang
Jinping Jia
Laufey T. Amundadottir
ResearchOpen Access27 Apr 2017
Nature Communications

Volume: 8, P: 1-17
Modification of Ultra-violet Erythema by Epidermal Stripping

MARK ALLEN EVERETT
JAMES A. WALTERMIRE
ROBERT SAYRE
Research20 Feb 1965
Nature

Volume: 205, P: 812-813
Viscosity and Molecular Structure

H. MARK
R. SIMHA
Research03 Aug 1940
Nature

Volume: 146, P: 167-168
Acoustical Phonon Spectra of Biological Polymers

WARNER L. PETICOLAS
MARK W. DOWLEY
Research22 Oct 1966
Nature

Volume: 212, P: 400-401
Shared heritability and functional enrichment across six solid cancers

Similarities in cancers can be studied to interrogate their etiology. Here, the authors use genome-wide association study summary statistics from six cancer types based on 296,215 cases and 301,319 controls of European ancestry, showing that solid tumours arising from different tissues share a degree of common germline genetic basis.

Xia Jiang
Hilary K. Finucane
Sara Lindström
ResearchOpen Access25 Jan 2019
Nature Communications

Volume: 10, P: 1-23
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

Multi-ancestry genome-wide analyses identify 95 loci associated with post-traumatic stress disorder and implicate candidate genes, pathways and neurobiological systems underlying its pathophysiology.

Caroline M. Nievergelt
Adam X. Maihofer
Karestan C. Koenen
Research18 Apr 2024
Nature Genetics

Volume: 56, P: 792-808
One-quarter of freshwater fauna threatened with extinction

A global multi-taxon extinction risk assessment of freshwater fauna for The IUCN Red List of Threatened Species finds one-quarter of species to be at high risk of extinction.

Catherine A. Sayer
Eresha Fernando
William R. T. Darwall
ResearchOpen Access08 Jan 2025
Nature

Volume: 638, P: 138-145
Efficient green methanol synthesis from glycerol

Impure glycerol is obtained as a significant by-product of biodiesel production. Now it is shown that this crude glycerol can be reacted with water over very simple basic or redox oxide catalysts to produce methanol in high yields, together with other useful chemicals, in a one-step low pressure process.

Muhammad H. Haider
Nicholas F. Dummer
Graham J. Hutchings
Research14 Sept 2015
Nature Chemistry

Volume: 7, P: 1028-1032
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson
Ambereen Ali
Douglas K. Miller
Research06 Jul 1995
Nature

Volume: 376, P: 37-43
Correction: Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

Jun Fang
Jinping Jia
Laufey T. Amundadottir
Amendments and CorrectionsOpen Access05 Mar 2018
Nature Communications

Volume: 9, P: 1-2
Cosmogenic helium in a terrestrial igneous rock

Mark D. Kurz
Research03 Apr 1986
Nature

Volume: 320, P: 435-439
Society should decide on UK badger cull

Mark Woolhouse
James Wood
Correspondence26 Jun 2013
Nature

Volume: 498, P: 434
A ballistic graphene superconducting microwave circuit

Encapsulated graphene Josephson junctions are promising for microwave quantum circuits but so far haven’t been explored. Here, Schmidt and Jenkins et al. observe a gate-tunable Josephson inductance in a microwave circuit based on a ballistic graphene Josephson junction embedded in a superconducting cavity.

Felix E. Schmidt
Mark D. Jenkins
Gary A. Steele
ResearchOpen Access04 Oct 2018
Nature Communications

Volume: 9, P: 1-7
Observations of dilatancy-induced polarization anomalies and earthquake prediction

Stuart Crampin
Russ Evans
Alistair Miller
Research28 Aug 1980
Nature

Volume: 286, P: 874-877
Burden of illness among patients with asthma prescribed inhaled corticosteroids/long-acting β₂-agonists

Shiyuan Zhang
Alexandrosz Czira
Mark Small
ResearchOpen Access26 Feb 2025
npj Primary Care Respiratory Medicine

Volume: 35, P: 1-10
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

Fine-mapping of causal variants and integration of epigenetic and chromatin conformation data identify likely target genes for 150 breast cancer risk regions.

Laura Fachal
Hugues Aschard
Alison M. Dunning
Research07 Jan 2020
Nature Genetics

Volume: 52, P: 56-73
A comprehensive genetic map of the human genome based on 5,264 microsatellites

Colette Dib
Sabine Fauré
Jean Weissenbach
Research14 Mar 1996
Nature

Volume: 380, P: 152-154
Contribution of C1- and F-bearing gases to the atmosphere by volcanoes

Robert B. Symonds
William I. Rose
Mark H. Reed
Research01 Aug 1988
Nature

Volume: 334, P: 415-418
A genetic map of the mouse with 4,006 simple sequence length polymorphisms

William F. Dietrich
Joyce C. Miller
Eric S. Lander
Research01 Jun 1994
Nature Genetics

Volume: 7, P: 220-245
The Friedreich's ataxia gene encodes a novel phosphatidylinositol–4–phosphate 5–kinase

Jaime J. Carvajal
Mark A. Pook
Susan Chamberlain
Research01 Oct 1996
Nature Genetics

Volume: 14, P: 157-162
Correction: A comprehensive genetic map of the mouse genome

William F. Dietrich
Joyce Miller
Eric S. Lander
Amendments and Corrections09 May 1996
Nature

Volume: 381, P: 172
The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

Feroz R. Papa
Mark Hochstrasser
Research25 Dec 1993
Nature

Volume: 366, P: 313-319
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism

Mark W. Sornson
Wei Wu
Michael G. Rosenfeld
Research28 Nov 1996
Nature

Volume: 384, P: 327-333
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction

A national prospective study of patients requiring hospitalization for COVID-19 demonstrates global cognitive deficits at 1 year, associated with elevated brain injury markers and reduced gray matter volume.

Greta K. Wood
Brendan F. Sargent
E. Charles Leek
ResearchOpen Access23 Sept 2024
Nature Medicine

Volume: 31, P: 245-257

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