Nature Search

Fine-mapping genomic loci refines bipolar disorder risk genes

This study used fine-mapping to analyze genetic regions associated with bipolar disorder, identifying specific risk genes and providing new insights into the biology of the condition that may guide future research and treatment approaches.

Maria Koromina
Ashvin Ravi
Niamh Mullins
ResearchOpen Access25 Jun 2025
Nature Neuroscience

P: 1-11
Genomics yields biological and phenotypic insights into bipolar disorder

Using multi-ancestry genome-wide association study and fine-mapping, 298 loci and 36 credible genes are identified in the aetiology of bipolar disorder.

Kevin S. O’Connell
Maria Koromina
Dan Siskind
Research22 Jan 2025
Nature

Volume: 639, P: 968-975
Erratum: The oxygen isotope effect in Ba_0.625K_0.375BiO₃

D. G. Hinks
D. R. Richards
A. W. Mitchell
Amendments and Corrections08 Dec 1988
Nature

Volume: 336, P: 604
Morphometric and isozyme evidence for the hybrid origin of a new tetraploid radiate groundsel in York, England

Judith A Irwin
Richard J Abbott
Research01 Nov 1992
Heredity

Volume: 69, P: 431-439
Britain in leaf

Alan Mitchell
Books & Arts03 Dec 1981
Nature

Volume: 294, P: 495-496
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

Genome-wide association analyses of 41,917 bipolar disorder cases and 371,549 controls of European ancestry provide new insights into the etiology of this disorder and identify novel therapeutic leads and potential opportunities for drug repurposing.

Niamh Mullins
Andreas J. Forstner
Ole A. Andreassen
Research17 May 2021
Nature Genetics

Volume: 53, P: 817-829
Pollinator movements and the polymorphism for outcrossing rate at the ray floret locus in Groundsel, Senecio vulgaris L.

Richard J Abbott
Judith A Irwin
Research01 Apr 1988
Heredity

Volume: 60, P: 295-298
Multiple origins and genetic diversity in the newly arisen allopolyploid species, Senecio cambrensis Rosser (Compositae)

Paul A Ashton
Richard J Abbott
Research01 Jan 1992
Heredity

Volume: 68, P: 25-32
Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

Lisa Coussens
Charles Van Beveren
Axel Ullrich
Research20 Mar 1986
Nature

Volume: 320, P: 277-280
Genetic diversity for esterases in the recently evolved stabilized introgressant, Senecio vulgaris L. var. hibernicus Syme, and its parental taxa S. vulgaris L. var. vulgaris L. and S. squalidus L.

Richard J Abbott
Judith A Irwin
Paul A Ashton
Research01 Jun 1992
Heredity

Volume: 68, P: 547-556
Morphometric signals of population decline in diademed sifakas occupying degraded rainforest habitat in Madagascar

Mitchell T. Irwin
Karen E. Samonds
Kenneth E. Glander
ResearchOpen Access19 Jun 2019
Scientific Reports

Volume: 9, P: 1-14
Absence of a radiate morph bearing self-incompatible ray florets from Edinburgh populations of Senecio vulgaris L.

Richard J Abbott
Judith A Irwin
David F Forbes
Research01 Jun 1990
Heredity

Volume: 64, P: 391-393
Species stabilization for mouse lemurs

A systematic assessment of species diversity in Madagascar’s mouse lemurs provides multifaceted guidelines for species recognition in the era of an explosion of genetic data, while still recognizing the relevance of species diversity for conservation.

Mitchell Irwin
News & Views27 Sept 2024
Nature Ecology & Evolution

Volume: 9, P: 15-16
Molecular systematics of the genus Senecio L. I: Hybridization in a British polyploid complex

Stephen A Harris
Ruth Ingram
Research01 Jul 1992
Heredity

Volume: 69, P: 1-10
The fate of Madagascar’s rainforest habitat

Climate change and habitat loss threaten species survival in Madagascar. Ruffed lemurs, a representative species in the eastern rainforest, could lose 38–93% of their habitat from climate change and deforestation by 2070; protecting areas from deforestation is necessary to protect Malagasy biodiversity.

Toni Lyn Morelli
Adam B. Smith
Andrea L. Baden
Research23 Dec 2019
Nature Climate Change

Volume: 10, P: 89-96
Global phylogeography and ancient evolution of the widespread human gut virus crAssphage

Here, the authors describe the global distribution of crAssphage, its presence in Old-World and New-World primates, and its association with gut bacterial communities and dietary factors, providing insights into the origin, evolution and epidemiology of human gut crAssphage.

Robert A. Edwards
Alejandro A. Vega
Bas E. Dutilh
Research08 Jul 2019
Nature Microbiology

Volume: 4, P: 1727-1736
The beet R locus encodes a new cytochrome P450 required for red betalain production

Alan Lloyd and colleagues report the mapping of a gene encoding a novel cytochrome P450, CYP76AD1, to the classic R locus in beet that is responsible for red versus yellow pigment.

Gregory J Hatlestad
Rasika M Sunnadeniya
Alan M Lloyd
Research03 Jun 2012
Nature Genetics

Volume: 44, P: 816-820
Glucocorticoid-induced Cushing syndrome increases the risk of cardiovascular events

Fiona Mitchell
Research Highlights21 Aug 2012
Nature Reviews Endocrinology

Volume: 8, P: 563
Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Empirically based models of disease progression in familial frontotemporal dementia reveal the relative ordering of clinical, neuroimaging, and fluid biomarker changes and facilitate novel clinical trial designs

Adam M. Staffaroni
Melanie Quintana
Sónia Afonso
Research22 Sept 2022
Nature Medicine

Volume: 28, P: 2194-2206
A high-resolution map of human evolutionary constraint using 29 mammals

Kerstin Lindblad-Toh
Manuel Garber
Manolis Kellis
ResearchOpen Access12 Oct 2011
Nature

Volume: 478, P: 476-482
Gene transfer to plants by diverse species of bacteria

Wim Broothaerts
Heidi J. Mitchell
Richard A. Jefferson
Research10 Feb 2005
Nature

Volume: 433, P: 629-633
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Regulation of epidermal apoptosis and DNA repair by E2F1 in response to ultraviolet B radiation

Thomas R Berton
David L Mitchell
David G Johnson
Research07 Feb 2005
Oncogene

Volume: 24, P: 2449-2460
Reproductive isolation of a new hybrid species, Senecio eboracensis Abbott & Lowe (Asteraceae)

A J Lowe
R J Abbott
Research10 Mar 2004
Heredity

Volume: 92, P: 386-395
Introgressive origin of the radiate groundsel, Senecio vulgaris L. var. hibernicus Syme: Aat-3 evidence

Richard J Abbott
Paul A Ashton
David G Forbes
Research01 May 1992
Heredity

Volume: 68, P: 425-435
Banter is no laughing matter in the dental setting

Kathryn Pitters
Special Features10 Oct 2022
BDJ In Practice

Volume: 35, P: 34
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Rachel L O’Connell
Tim Rattay
Mohammed Mustafa
ResearchOpen Access29 Mar 2019
British Journal of Cancer

Volume: 120, P: 883-895
A gravitational-wave standard siren measurement of the Hubble constant

The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

B. P. Abbott
R. Abbott
M. Serra-Ricart
Research16 Oct 2017
Nature

Volume: 551, P: 85-88
Correction: Impact of the COVID-19 pandemic on breast cancer patient pathways and outcomes in the United Kingdom and the Republic of Ireland – a scoping review

Lynne Lohfeld
Meenakshi Sharma
Charlene M. McShane
Amendments and CorrectionsOpen Access25 Jul 2024
British Journal of Cancer

Volume: 131, P: 778
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Levels of Par-1 kinase determine the localization of Bruchpilot at the Drosophila neuromuscular junction synapses

Kara R. Barber
Martin Hruska
Yogesh P. Wairkar
ResearchOpen Access31 Oct 2018
Scientific Reports

Volume: 8, P: 1-13
Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

Rajiv V. Dave
Baek Kim
Zaid Al-Ishaq
ResearchOpen Access25 Mar 2021
British Journal of Cancer

Volume: 124, P: 1785-1794
Thymine DNA glycosylase as a novel target for melanoma

Pietro Mancuso
Rossella Tricarico
Alfonso Bellacosa
ResearchOpen Access23 Jan 2019
Oncogene

Volume: 38, P: 3710-3728
Introducing IsoMad, a compilation of isotopic datasets for Madagascar

Sean W. Hixon
Ricardo Fernandes
Brooke E. Crowley
ResearchOpen Access09 Aug 2024
Scientific Data

Volume: 11, P: 1-8
Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma

T M Wright
A R Brannon
W K Rathmell
Research18 May 2009
Oncogene

Volume: 28, P: 2513-2523
Correction to: Thymine DNA glycosylase as a novel target for melanoma

Pietro Mancuso
Rossella Tricarico
Alfonso Bellacosa
Amendments and Corrections03 May 2022
Oncogene

Volume: 41, P: 3300-3301
Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

Maja Kopczynska
Harry Unwin
Judith E. Hall
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Impact of the COVID-19 pandemic on breast cancer patient pathways and outcomes in the United Kingdom and the Republic of Ireland – a scoping review

Lynne Lohfeld
Meenakshi Sharma
Charlene M. McShane
ReviewsOpen Access04 May 2024
British Journal of Cancer

Volume: 131, P: 619-626
Distinct cord blood C-peptide, adipokine, and lipidomic signatures by in utero HIV exposure

Jennifer Jao
Lauren C. Balmert
Irwin J. Kurland
Research26 Aug 2021
Pediatric Research

Volume: 92, P: 233-241
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Preventing bronchopulmonary dysplasia: new tools for an old challenge

María Álvarez-Fuente
Laura Moreno
Maria Jesús del Cerro
Reviews21 Nov 2018
Pediatric Research

Volume: 85, P: 432-441
Your duties as a professional witness

Tina Lakhani
Special Features08 Mar 2021
BDJ In Practice

Volume: 34, P: 36-37
How to respond if you are stopped by a police officer

Tina Lakhani
Special Features08 Feb 2021
BDJ In Practice

Volume: 34, P: 27-28

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