Search

Upon NIR illumination, photocleavable complexes release rapamycin, reactivating dCas9 via fragment reassociation to enable sgRNA-guided gene regulation with spatial control, allowing precise “writing” with NIR light.

Measurements of fission fragments for 100 fissioning systems are used to map an asymmetric fission island, providing evidence for the role played by the deformation induced by a closed 36-proton shell.

Engineering of the spatial distribution of currents in a semiconductor is demonstrated using vectorial arrangement of optical fields, enabling an ultrafast magnetic field source.

This study presents a stable and efficient photoelectrochemical system for nitrate reduction to ammonia using metal catalysts on GaN/Si photoelectrodes, offering valuable insights into catalyst design for sustainable ammonia production driven by solar energy.

The genomic landscape of diffuse gliomas remains to be characterised. Here, the authors perform whole genome sequencing of 403 tumours and identify recurrent coding and non-coding genetic mutations, their associations with clinical outcomes and potential therapeutic targets.

Surface structures can have an important effect on the traits of two-dimensional electron liquids. Here, the authors demonstrate how the surface terminations of SrTiO₃(001) affect the mechanism and properties of the two-dimensional electron liquid.

This study examines the history of North Atlantic deep-water masses, as recorded in marine sediments. Major lithological changes and increased rate of deposition reveal that stronger deep-ocean circulation initiated 3.6 million years ago.

Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their molecular details and provides tools for further studies in pea genetics, functional genomics and crop improvement.

The nature of the superconductivity in the kagome metals AV₃Sb₅ (A = K, Rb, Cs) remains under debate. Here, using muon spin spectroscopy, the authors find that the superconductivity in RbV₃Sb₅ and KV₃Sb₅ evolves from nodal to nodeless with increasing pressure and the superconducting state breaks time-reversal symmetry after suppression of the charge order.

Extreme magnetoresistance is characterized by a large and non-saturating magnetoresistance. Typically, it is observed in materials with compensated bandstructures, however, here, Christensen et al demonstrate a large and non-saturating magnetoresistance in a γAl2O3/SrTiO3 heterostructure, which is related to disorder, rather than the materials bandstructure.

Colloidal self-assembly at liquid interfaces has important emulsion applications, for food, household or personal care products, and drug encapsulation. Here, the authors develop a method of forming patchy heterogeneous capsules by electro-coalescence of multiple liquid drops.

Polynuclear magnetic molecular complexes show promise as electrically controllable spin qubits. Here the authors report evidence of spin-electric transitions in the Fe3 triangle and propose it as a generalized exchange qubit, combining characteristics of spin-chirality and partial-spin sum qubits.

The topological character of electrons in semimetals subtly influences their bulk properties, leading typically to weak experimental signatures. Here, Moll et al. report a distinctive anomaly in the magnetic torque upon entering quantum limit state in the Weyl semimetal NbAs, which only appears due to the presence of Weyl fermions.

Plasma turbulence is the main driver to deteriorate the performance of fusion power plants. This work presents an unprecedented comparison of plasma turbulence between experiment and simulation, proving that the gyrokinetic model GENE reached a high level of maturity to predict core turbulence.

GIANT, a genetically informed brain atlas, integrates genetic heritability with neuroanatomy. It shows strong neuroanatomical validity and surpasses traditional atlases in discovery power for brain imaging genomics.

Water is vital for ion transport in anion exchange membranes (AEMs). Here, the authors used electrochemical impedance, ultrafast spectroscopy, and molecular models to reveal how water arrangements affect bromide ion transport in state-of-the-art AEMs, offering insights for better membrane design.

The kagome magnet Co₃Sn₂S₂ has complex magnetic behaviour and a topological band structure that yields a large anomalous Hall effect. Guguchia et al. find phase separation between ferro- and anti-ferromagnetic orders and that the volume-wise competition controls the anomalous Hall conductivity

The relationship between lipid dyshomeostasis and tau pathology in FTLD and AD remains unclear. Here, the authors demonstrate that GRAMD1B contributes to lipid dyshomeostasis, autophagy impairment, and tau hyperphosphorylation in neurons.

The study of phase transitions in quantum ferromagnets has shown that the approach to a continuous quantum ferromagnetic transition is typically interrupted by either a tricritical point or a new magnetic phase. Here the authors show that LaCrGe₃ exhibits both these features in its phase diagram.

During the last deglaciation the Cordilleran Ice Sheet experienced semi-continuous meltwater events between about 20,000 and 17,000 years ago, according to a terrestrial cave sediment record that has been described and dated.

The imaging of magnetic domains in three-dimensional solids has been hampered by a lack of suitable methods. The authors show that Talbot-Lau neutron tomography is capable of visualizing the ___domain structure of an iron silicide bulk crystal.

Magnetite provides a valuable record of the Earth's geomagnetic history. Here, Almeida et al. combine electron microscopy and energy-loss spectroscopy to study the effects of in situoxidation on the magnetization fidelity and crystalline phase of pseudo-single ___domain magnetite grains.

Controlling supercurrent pathways in a Josephson junction can lead to new functionalities. Here, Lahabi et al. demonstrate the tailoring of two distinct supercurrent channels in a ferromagnetic disk containing a magnetic vortex.

Magnetic vortices in thin ferromagnetic films possess a core with out-of-plane magnetization whose polarity can be manipulated by magnetic fields or currents for technological applications. Here, the authors demonstrate local control of the core polarity in NiFe films via an imprinted maze ___domain pattern.

Plasmonic nanostructures can be used to manipulate objects larger than the wavelength of light but create thermal heating. In this work, the trapping and controlled rotation of nanoparticles is demonstrated using a plasmonic nanotweezer with a heat sink, predicting a reduction in heating compared with previous designs.

Targeted IKZF2 degradation represents a potential therapeutic strategy for cancer immunotherapy. Here, the authors described the discovery of PVTX-405 as a potent, highly selective, and orally efficacious IKZF2 molecular glue degrader and their preclinical data support the clinical development of PVTX-405.

Dynamic Jahn-Teller effect is rarely realized in condensed matter systems. Here, the authors demonstrate its occurrence in Ba₂MgReO₆, a 5d¹ double perovskite, using resonant inelastic x-ray scattering, thermodynamic measurements and quantum chemistry calculations.

Previous understanding of the coupling between ferroelectric structure and magnetic texture in BiFeO₃ has relied on mesoscale measurements. Here, the authors image coupling directly, showing a complex spin cycloid controlled with electric field.

X-ray absorption imaging is used for early breast cancer detection but can barely identify the morphology of microcalcifications—a possible indicator of cancer. Wang et al.develop a technique to non-invasively classify different types of microcalcifications and achieve 100% sensitivity on phantom data.

Loss-of-function variants in thyroid hormone transporter MCT8 cause a neurodevelopmental and metabolic disorder. Here the authors identify genotype-phenotype relationships, advance insights in MCT8 (dys)function and create a pathogenicity-severity variant classifier.

Characterizing the interference of phonons at the single-molecule level remains a challenging task. Here, the authors observe and characterize destructive phonon interference in molecular junctions at room temperature.

Droplet microfluidic tools with single-cell resolution and high-throughput screening capacities remain scarce. Here, the authors propose NOVAsort, a next-generation droplet sorter that can discern droplets based on both size and fluorescence, which can overcome common problems with conventional sorters.

Each 100 mm increase in irrigation reduces the heat sensitivity of maize by 7.6% in the Ogallala Aquifer, United States, but a 67% increase in irrigation would be needed to offset a 26% yield decline in a high-emissions scenario, according to a meta-analysis of maize field experiments.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

CrI₃ is a popular van der Waals magnet that exhibits anomalous magnetic properties between bulk and thin layers due to different crystal symmetry. Here, the authors report the coexistence of different magnetostructural phases over the entire range of temperatures, solving a long-standing puzzle.

Pigs and farmers in Uganda’s semi-intensive systems carry more antimicrobial resistant bacteria and face higher transmission risks than those in free-range systems, suggesting intensified pig farming may elevate antimicrobial resistance, based on 877 fecal samples from 35 pig-farmer pairs.

Experimental approaches that can directly measure spin-lattice coupling are rare. Here, authors report direct observation of the coupling of the phonon and magnon dynamics of a coherently driven electromagnon in a multiferroic hexaferrite using time-resolved X-ray diffraction. (277 characters in total).

An understanding of how quantum spin liquids arise in frustrated magnets at low temperatures remains elusive. Here the authors demonstrate a pressure-driven ferromagnetic transition out of a quantum spin liquid phase in the pyrochlore Yb₂Ti₂O₇, highlighting its proximity to a phase boundary.

Genomic and phenomic screens of 827 wheat landraces from the A. E. Watkins collection provide insight into the wheat population genetic background, unlocking many agronomic traits and revealing haplotypes that could potentially be used to improve modern wheat cultivars.