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Nature Neuroscience (2)

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Advanced filters: Author: Pengwei Luan Clear advanced filters

An axonal brake on striatal dopamine output by cholinergic interneurons

Cholinergic interneurons act at nicotinic receptors to depress dopamine release, interrupting its relationship to dopamine neuron firing and supporting an inverse scaling of dopamine release according to cholinergic activity.

Yan-Feng Zhang
Pengwei Luan
Stephanie J. Cragg
ResearchOpen Access13 Mar 2025
Nature Neuroscience

Volume: 28, P: 783-794
Spatiotemporally selective astrocytic ATP dynamics encode injury information sensed by microglia following brain injury in mice

The mechanisms regulating microglial response to brain injury are unclear. Here, the authors show that astrocytic ATP dynamics encode injury information and trigger microglia response affecting the tissue damage and recovery of function following injury in mice.

Yue Chen
Pengwei Luan
Miao Jing
Research11 Jun 2024
Nature Neuroscience

Volume: 27, P: 1522-1533

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An axonal brake on striatal dopamine output by cholinergic interneurons

Spatiotemporally selective astrocytic ATP dynamics encode injury information sensed by microglia following brain injury in mice

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