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Showing 51–100 of 131 results

Advanced filters: Author: Pin Ge Clear advanced filters

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice

Sensitisation of dorsal root ganglia neurons contributes to neuropathic pain. Here the authors demonstrate the cytokine FL contributes to sensitisation of DRGs via its receptor FLT3 expressed on neurons, and identify a novel FLT3 inhibitor that attenuates neuropathic pain in mice.

Cyril Rivat
Chamroeun Sar
Jean Valmier
ResearchOpen Access12 Mar 2018
Nature Communications

Volume: 9, P: 1-13
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway

Mutations in PHF8 gene are genetically associated with X-linked mental retardation. Here, Chen et al. show that Phf8 KO mouse have cognitive and synaptic plasticity impairment, and pharmacological inhibition of mTOR signaling can partially alleviate such defects.

Xuemei Chen
Shuai Wang
Charlie Degui Chen
ResearchOpen Access09 Jan 2018
Nature Communications

Volume: 9, P: 1-11
No-vaxxers are different in public good games

Marcello Basili
Alessio Muscillo
Paolo Pin
ResearchOpen Access28 Oct 2022
Scientific Reports

Volume: 12, P: 1-8
Systems analysis of EGF receptor signaling dynamics with microwestern arrays

Microwestern arrays combine the advantages of scalability of reverse phase protein arrays and the information content of western blotting for analyzing protein abundance and modification state with high sensitivity and throughput. The method is demonstrated for analyzing phosphorylation state changes in the EGF receptor signaling network using Bayesian network modeling.

Mark F Ciaccio
Joel P Wagner
Richard B Jones
Research24 Jan 2010
Nature Methods

Volume: 7, P: 148-155
PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans

Catherine André, Judith Fischer and colleagues report that mutations in PNPLA1 cause congenital ichthyosis in humans and golden retriever dogs. Their findings suggest a role for PNPLA1 in the formation of the epidermal lipid barrier.

Anaïs Grall
Eric Guaguère
Judith Fischer
Research15 Jan 2012
Nature Genetics

Volume: 44, P: 140-147
A Phase IIa clinical trial to evaluate the effects of anti-retroviral therapy in Alzheimer’s disease (ART-AD)

A. Campbell Sullivan
Gabrielle Zuniga
Bess Frost
ResearchOpen Access12 Mar 2025
npj Dementia

Volume: 1, P: 1-9
Inverse Correlation Between Left Atrial Appendage Function and CHA₂DS₂-VASc Score in Patients with Atrial Flutter

Mei-Yao Wu
Yen-Nien Lin
Kuan-Cheng Chang
ResearchOpen Access28 Nov 2019
Scientific Reports

Volume: 9, P: 1-9
High prevalence of APOA1/C3/A4/A5 alterations in luminal breast cancers among young women in East Asia

Ching-Hung Lin
Ruby Yun-Ju Huang
Ann-Lii Cheng
ResearchOpen Access05 Jul 2021
npj Breast Cancer

Volume: 7, P: 1-10
Tunable Schottky barrier in graphene/graphene-like germanium carbide van der Waals heterostructure

Sake Wang
Jyh-Pin Chou
Minglei Sun
ResearchOpen Access26 Mar 2019
Scientific Reports

Volume: 9, P: 1-7
ERK/c-Jun Recruits Tet1 to Induce Zta Expression and Epstein-Barr Virus Reactivation through DNA Demethylation

Wei Zhang
Dongjie Han
Jianguo Wu
ResearchOpen Access06 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer

Jihong Wang
Joseph Weygand
Jinyuan Zhou
ResearchOpen Access27 Jul 2016
Scientific Reports

Volume: 6, P: 1-7
The extracellular SEMA ___domain attenuates intracellular apoptotic signaling of semaphorin 6A in lung cancer cells

Cheng-Ying Shen
Ya-Chu Chang
Eric Y. Chuang
ResearchOpen Access05 Dec 2018
Oncogenesis

Volume: 7, P: 1-10
Mapping native disulfide bonds at a proteome scale

A workflow for preserving disulfide links in proteins in conjunction with pLink-SS enables the analysis of disulfide bonds across the proteome.

Shan Lu
Sheng-Bo Fan
Meng-Qiu Dong
Research09 Feb 2015
Nature Methods

Volume: 12, P: 329-331
Comprehensive phenotypic assessment of nonsense mutations in mitochondrial ND5 in mice

Sanghun Kim
Seul Gi Park
Hyunji Lee
ResearchOpen Access01 Nov 2024
Experimental & Molecular Medicine

Volume: 56, P: 2395-2408
Macrophage Migration Inhibitory Factor Acts as the Potential Target of a Newly Synthesized Compound, 1-(9′-methyl-3′-carbazole)-3, 4-dihydro-β-carboline

Pin-Hao Ko
Ya-Ching Shen
Liang-Chuan Lai
ResearchOpen Access14 Feb 2019
Scientific Reports

Volume: 9, P: 1-12
Thermal conductivity of materials under pressure

Mastering thermal conductivities of materials under pressure is extremely important for managing thermal processes, understanding the thermal transport mechanisms and for potential technological applications. This Review surveys the progresses in technique developments, research results and scientific implications in this field.

Yan Zhou
Zuo-Yuan Dong
Xiao-Jia Chen
Reviews21 Feb 2022
Nature Reviews Physics

Volume: 4, P: 319-335
Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans

Lin Fan
Junwei Liu
Jian’an Wang
ResearchOpen Access15 Mar 2024
Cell Research

Volume: 34, P: 407-427
Theoretical error performance analysis for variational quantum circuit based functional regression

Jun Qi
Chao-Han Huck Yang
Min-Hsiu Hsieh
ResearchOpen Access09 Jan 2023
npj Quantum Information

Volume: 9, P: 1-10
Bisphosphonate conjugation enhances the bone-specificity of NELL-1-based systemic therapy for spaceflight-induced bone loss in mice

Pin Ha
Jin Hee Kwak
Chia Soo
ResearchOpen Access18 Sept 2023
npj Microgravity

Volume: 9, P: 1-15
Multiparametric MRI–based radiomic models for early prediction of response to neoadjuvant systemic therapy in triple-negative breast cancer

Rania M. Mohamed
Bikash Panthi
Gaiane M. Rauch
ResearchOpen Access12 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
Regulator of calcineurin 1 is a novel RNA-binding protein to regulate neuronal apoptosis

Yan Yun
Yun Zhang
Xiulian Sun
Research27 Aug 2019
Molecular Psychiatry

Volume: 26, P: 1361-1375
Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells

Hsing-Hua Chao
Jun-Liang Luo
Liang-Chuan Lai
ResearchOpen Access20 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-15
Prediction of HPC compressive strength based on machine learning

Libing Jin
Jie Duan
Pin Zhou
ResearchOpen Access22 Jul 2024
Scientific Reports

Volume: 14, P: 1-18
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus–related hepatocellular carcinoma

Long Yu and colleagues report a genome-wide association study for hepatitis B virus–related hepatocellular carcinoma (HBV-HCC). They report that genetic variants in STAT4 and HLA-DQ genes confer risk of HBV-HCC.

De-Ke Jiang
Jielin Sun
Long Yu
Research16 Dec 2012
Nature Genetics

Volume: 45, P: 72-75
Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro

Li Sun
Hong-xiang Wang
Zhi-chao Chen
Research30 Dec 2013
Acta Pharmacologica Sinica

Volume: 35, P: 381-393
Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles

Mikołaj Piotr Zaborowski
Pike See Cheah
Xandra O. Breakefield
ResearchOpen Access22 Nov 2019
Scientific Reports

Volume: 9, P: 1-16
Quantifying attention in children with intellectual and developmental disabilities through multicenter electrooculogram signal analysis

Shi-yi Qi
Si-jia Zhang
Dong Lin
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-17
A marine photosynthetic microbial cell factory as a platform for spider silk production

Foong et al. demonstrate production of spider dragline silk proteins in Rhodovulum sulfidophilum, a marine photosynthetic purple bacterium. This platform generates promise for the sustainable production of valuable biocompounds in photosynthetic organisms.

Choon Pin Foong
Mieko Higuchi-Takeuchi
Keiji Numata
ResearchOpen Access08 Jul 2020
Communications Biology

Volume: 3, P: 1-8
The association between body mass index and osteoporosis in a Taiwanese population: a cross-sectional and longitudinal study

Chao-Tse Chiu
Jia-In Lee
Jiun-Hung Geng
ResearchOpen Access12 Apr 2024
Scientific Reports

Volume: 14, P: 1-9
Direct coupling of detergent purified human mGlu₅ receptor to the heterotrimeric G proteins Gq and Gs

Chady Nasrallah
Karine Rottier
Guillaume Lebon
ResearchOpen Access13 Mar 2018
Scientific Reports

Volume: 8, P: 1-13
SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication

Pan Pan
Weiwei Ge
Jianguo Wu
ResearchOpen Access09 May 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-15
A missense variant in the nuclear localization signal of DKC1 causes Hoyeraal-Hreidarsson syndrome

Chia-Mei Chu
Hsin-Hui Yu
Chi-Kang Tseng
ResearchOpen Access30 Oct 2022
npj Genomic Medicine

Volume: 7, P: 1-12
Differences in lobar microbleed topography in cerebral amyloid angiopathy and hypertensive arteriopathy

Pin-Yan Kuo
Hsin-Hsi Tsai
Li-Kai Tsai
ResearchOpen Access15 Feb 2024
Scientific Reports

Volume: 14, P: 1-9
Nano-encapsulated Escherichia coli Divisome Anchor ZipA, and in Complex with FtsZ

Sarah C. Lee
Richard Collins
Timothy R. Dafforn
ResearchOpen Access10 Dec 2019
Scientific Reports

Volume: 9, P: 1-16
A method for detergent-free isolation of membrane proteins in their local lipid environment

This protocol from Lee et al. describes a method for the extraction of membrane proteins in their native lipid environment using styrene maleic anhydride (SMA) co-polymer. The method is applicable to both prokaryotic and eukaryotic expression systems.

Sarah C Lee
Tim J Knowles
Timothy R Dafforn
Protocols02 Jun 2016
Nature Protocols

Volume: 11, P: 1149-1162
Novel Crabtree negative yeast from rumen fluids can improve rumen fermentation and milk quality

Chanon Suntara
Anusorn Cherdthong
Pin Chanjula
ResearchOpen Access18 Mar 2021
Scientific Reports

Volume: 11, P: 1-13
GLIS2 promotes colorectal cancer through repressing enhancer activation

Jie Yao
Pin-Ji Lei
Min Wu
ResearchOpen Access01 Jun 2020
Oncogenesis

Volume: 9, P: 1-15
Involvement of 8-O-acetylharpagide for Ajuga taiwanensis mediated suppression of senescent phenotypes in human dermal fibroblasts

Wei-Hsiang Hsu
Bing-Ze Lin
Yi-Jang Lee
ResearchOpen Access12 Nov 2020
Scientific Reports

Volume: 10, P: 1-14
WFDC3 inhibits tumor metastasis by promoting the ERβ-mediated transcriptional repression of TGFBR1 in colorectal cancer

Tianqi Liu
Min Zhao
Xiangqian Su
ResearchOpen Access13 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-14
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities

Seiko Ikezu
Hana Yeh
Tsuneya Ikezu
ResearchOpen Access18 Feb 2020
Molecular Psychiatry

Volume: 26, P: 1808-1831
Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens

Chuen-Yu Cheng
Wei-Lin Tu
San-Yuan Huang
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-11
Integrated transcriptomic and proteomic analyses reveal potential mechanisms linking thermal stress and depressed disease resistance in the turbot Scophthalmus maximus

Xin Yue
Pin Huan
Baozhong Liu
ResearchOpen Access30 Jan 2018
Scientific Reports

Volume: 8, P: 1-13
C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Mei-Chun Lin
Pin-Hui Chien
Min-Chuan Huang
ResearchOpen Access21 Jun 2018
Oncogene

Volume: 37, P: 5780-5793
Children with severe neurological symptoms associated with SARS-CoV-2 infection during Omicron pandemic in China

Tao Zhang
Qiao-Feng Zhang
Chun-Feng Liu
Research21 Nov 2023
Pediatric Research

Volume: 95, P: 1088-1094
Isolation of Rhp-PSP, a member of YER057c/YjgF/UK114 protein family with antiviral properties, from the photosynthetic bacterium Rhodopseudomonas palustris strain JSC-3b

Pin Su
Tuizi Feng
Yong Liu
ResearchOpen Access04 Nov 2015
Scientific Reports

Volume: 5, P: 1-10
USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination

Prasanna Vasudevan Iyengar
Patrick Jaynes
Pieter Johan Adam Eichhorn
ResearchOpen Access05 Oct 2015
Scientific Reports

Volume: 5, P: 1-15
Hypofractionated stereotactic radiation therapy activates the peripheral immune response in operable stage I non-small-cell lung cancer

Ting Zhang
Haifeng Yu
Xiaojian Wang
ResearchOpen Access07 Jul 2017
Scientific Reports

Volume: 7, P: 1-10
The Comparative Studies of Binding Activity of Curcumin and Didemethylated Curcumin with Selenite: Hydrogen Bonding vs Acid-Base Interactions

Jiahn-Haur Liao
Tzu-Hua Wu
Shih-Hsiung Wu
ResearchOpen Access04 Dec 2015
Scientific Reports

Volume: 5, P: 1-12
Generation of clade- and symbiont-specific antibodies to characterize marker molecules during Cnidaria-Symbiodinium endosymbiosis

Kao-Jean Huang
Zi-Yu Huang
Hsing-Hui Li
ResearchOpen Access14 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
Combination of OipA, BabA, and SabA as candidate biomarkers for predicting Helicobacter pylori-related gastric cancer

Yu-Lin Su
Hsiang-Ling Huang
Lu-Ping Chow
ResearchOpen Access07 Nov 2016
Scientific Reports

Volume: 6, P: 1-12

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