Nature Search

A transcriptome-based human universal senescence index (hUSI) robustly predicts cellular senescence under various conditions

Wang et al. present the human universal senescence index (hUSI), a robust transcriptome-based tool that accurately predicts cellular senescence across diverse conditions, offering insights into aging and therapeutic strategies.

Jing Wang
Xiaolan Zhou
Ting Ni
ResearchOpen Access29 May 2025
Nature Aging

Volume: 5, P: 1159-1175
Ultrafast imaging of spontaneous symmetry breaking in a photoionized molecular system

The Jahn-Teller effect is the spontaneous symmetry breaking of the molecular structure caused by the coupling of electrons and nuclei. Here the authors use ultrafast Coulomb explosion imaging to map the evolution of the fundamental symmetry lowering process in photoionized methane within around 20fs.

Min Li
Ming Zhang
Peixiang Lu
ResearchOpen Access09 Jul 2021
Nature Communications

Volume: 12, P: 1-6
Warming-induced retreat of West Antarctic glaciers weakened carbon sequestration ability but increased mercury enrichment

This study reveals that Holocene warming and glacial retreat in West Antarctica reduced carbon sequestration but enhanced mercury burial in Ross Sea sediments, suggesting future warming could further accelerate carbon loss and mercury accumulation.

Chengzhen Zhou
Maodian Liu
Peter A. Raymond
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-14
A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation

Yi et al. report that EZH2 exerts a PRC2-independent function in nucleoli, where it bridges FBL and NOP56 to facilitate rRNA methylation and subsequent IRES-dependent translation.

Yang Yi
Yanqiang Li
Qi Cao
Research01 Apr 2021
Nature Cell Biology

Volume: 23, P: 341-354
China’s municipal wastewater policies enhanced seafood safety and offset health risks from atmospheric mercury emissions in the past four decades

Seafood methylmercury contamination is a global food safety issue. A model is developed to explore the impact of China’s municipal wastewater policies on seafood safety and reductions in methylmercury exposure.

Xingrui Cai
Mengqi Yang
Xuejun Wang
Research02 Jan 2025
Nature Food

Volume: 6, P: 182-195
Noninvasive, microbiome-based diagnosis of inflammatory bowel disease

Using ethnically and geographically diverse metagenomic data, the authors identify microbiota alterations associated with inflammatory bowel disease (IBD). They discover universal IBD-associated bacteria, which serve as the basis for a multibacteria biomarker panel that could support a noninvasive tool for IBD diagnosis.

Jiaying Zheng
Qianru Sun
Siew C. Ng
ResearchOpen Access04 Oct 2024
Nature Medicine

Volume: 30, P: 3555-3567
Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation

Dietary inulin fibre alters the composition and metabolism of gut microbiota, resulting in elevated levels of bile acids that subsequently trigger mucosal type 2 inflammation characterized by eosinophilia, with clinical implications for allergy and anti-helminth defence.

Mohammad Arifuzzaman
Tae Hyung Won
David Artis
Research02 Nov 2022
Nature

Volume: 611, P: 578-584
Rice life cycle-based global mercury biotransport and human methylmercury exposure

Fish consumption is considered to be the only significant dietary source of MeHg. Here the authors show that rice could also be a significant global dietary source, especially in South and Southeast Asia. International rice trade and joint ingestion of fish and rice could aggravate the MeHg exposure levels in many areas.

Maodian Liu
Qianru Zhang
Xuejun Wang
ResearchOpen Access14 Nov 2019
Nature Communications

Volume: 10, P: 1-14
Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor

The early signalling events that trigger initial T-cell receptor signalling are not clearly defined. Here the authors show that this occurs in two stages, the first between the CD8 coreceptor and CD3 requiring Lck association to CD8, while the second interaction requires binding of major histocompatibility molecules.

Javier Casas
Joanna Brzostek
Nicholas R. J. Gascoigne
Research27 Nov 2014
Nature Communications

Volume: 5, P: 1-11
Ultra-sensitive polarization-resolved black phosphorus homojunction photodetector defined by ferroelectric domains

Integrated polarization-sensitive photodetectors are important for sensing applications and optical communication. Here, the authors report the realization of 2D black phosphorus homojunction photodetectors defined by ferroelectric substrates, showing polarization ratios up to 288 and high responsivity in the near-infrared.

Shuaiqin Wu
Yan Chen
Jianlu Wang
ResearchOpen Access09 Jun 2022
Nature Communications

Volume: 13, P: 1-9
DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation

Chuanrong Zhao
Qianru Yang
Jing Zhou
ResearchOpen Access08 Jun 2023
npj Regenerative Medicine

Volume: 8, P: 1-17
Signaling from T cell receptors (TCRs) and chimeric antigen receptors (CARs) on T cells

Ling Wu
Qianru Wei
Nicholas R. J. Gascoigne
Reviews25 May 2020
Cellular & Molecular Immunology

Volume: 17, P: 600-612

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