Anterior prostate cancers, a group of impalpable neoplasms located in regions anterior to the urethra, are typically undersampled using conventional biopsy schemes, leading to a low detection rate and a high rate of false negatives. In this Review, the authors discuss the optimal diagnostic approaches to anterior prostate cancers and consider management and outcomes for patients with this form of prostate cancer.
- Sammy Gharbieh
- Joshua Mullin
- Ben Challacombe