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Metamaterial analogues of electromagnetically-induced transparency provide interesting optical components and applications. By actively tuning the dark mode of a metamaterial, Guet al. optically control its electromagnetically-induced transparency, showing tunable group delay of terahertz light.

Current seasonal flu vaccines hardly protect against emerging H5N1 such as clade 2.3.4.4b circulating in cattle. Here, the authors show that a single intranasal immunization of DelNS1-H5N1 vaccine candidates provides effective protection and sustained immunity against highly pathogenic avian influenza A viruses.

The patterning of perovskites faces stringent and complex fabrication processes. Here, authors realize erasable patterns based on mix-halide perovskite films via a direct photo-patterning technique, yielding multi-level pattern encoding technology.

The development of catalysts for practical asymmetric hydrogenation of ketones remains an important goal of synthetic organic chemistry. Here, an anionic iridium catalyst with excellent activity is reported and used in a hundred-kilogram-scale reduction as part of a route to chiral nicotine.

Membranes with a balance between water permeability and salt rejection are desirable, and can be developed through self-assembly and aggregation. Here, the authors report a hydrogen-bonding strategy in a nanoconfined space to give controlled crystallisation, for membranes for reverse osmosis.

Holographic techniques allow for the construction of 3D images by controlling the wave front of light beams. Huang et al.develop ultrathin plasmonic metasurfaces to provide 3D optical holographic image reconstruction in the visible and near-infrared regions for circularly polarized light.

Wang et al. demonstrate that the vascular smooth muscle cell–dependent expression of TRPM7, an ion channel with kinase function, increases the levels of calcium and zinc and, thus, increases the MMP2 activity and contributes to the formation of abdominal aortic aneurysm.

Atomically precise metal nanoclusters are an emerging class of precision nanomaterials and hold potential in many applications. Here, the authors devise a [Au₁₃Ag₁₂(PPh₃)₁₀Cl₈]⁺ nanocluster with two conformational isomers that can reversibly convert in response to temperature, and hence acts as a rotary nanomotor.

The exploration of heterogeneous interfaces between metal oxides has received limited attention. Here the authors demonstrated the creation of MnO₂-Mn_xCo_3-xO₄ interfaces through controlled chemical reduction processes, effectively altering electron distribution and yielding a superior catalyst for ethane oxidation.

The authors design an isothermal compressibility-assisted dynamic squeezing index perturbation (iCASE) methodology to improve enzyme stability and efficacy, which is combined with machine learning predictive models to advance enzyme optimization.

Non-glacier-fed lakes produce three times higher methane fluxes than glacier-fed lakes, although glacier-fed lakes have more stable microbial communities, according to microbiological analysis of water samples from the Tibetan Plateau.

Beyond the long-established chemolithoautotrophs, a new study by Shao et al. uncovers heterotrophic denitrifiers as previously concealed contributors to sulfur cycling, with profound implications for greenhouse gas mitigation.

Succinylation of PD-L1 by carnitine palmitoyltransferase 1A (CPT1A) in melanoma leads to its degradation and enhanced T cell-dependent killing in vitro. Increasing CPT1A levels synergizes with anti-CTLA-4 treatment to suppress tumor growth in a mouse melanoma model.

Spectroscopic signatures of magnetic response in topological materials remain very limited. Here, the authors observe a quasi-linear field dependent transverse magnetization and a non-saturating parallel magnetization in a Weyl semimetal TaAs under strong magnetic field, suggesting a signature of relativistic quasiparticles in topological materials.

The molecular phenotypic features of epithelial ovarian cancer (EOC) remain elusive. Here, the authors perform mass spectrometry-based proteomic profiling for 269 EOC patients and reveal molecularly distinct features and potential therapeutic targets among the histological subtypes of EOC.

A method to map the known tranverse photon spin of electromagnetic surface waves over to bulk modes is enabled thanks to bianisotropy.

Here, the authors demonstrate an analogue reversed Cherenkov radiation at mid-infrared frequencies in MoO₃, a natural hyperbolic material, and show that the radiation angle and the quality factor can be increased by stacking hBN layers on the MoO₃ surface.

Here, the authors demonstrate a multi-momentum transformation metasurface. The orbital angular momentum meta-transformer reconstructs different vortex beams into on-axis distinct patterns, and the linear momentum meta-transformer converts red, green and blue beams to vivid color images.

Single-atomic impurities may induce novel quantum state, but they are unexplored in topological magnets. Here, the authors report spin-down polarized bound states which further interact with neighboring states to form spin-orbit split quantized orbitals in a topological magnet Co₃Sn₂S₂.

The description of quasicrystal structures by only one repeating unit is desirable. Here the authors experimentally identify a quasi-unit-cell corresponding to a Lück decagon to describe the randomly ordered structure of a decagonal quasicrystalline phase.

Gasdermin E (GSDME) is a pyroptotic cell death effector and a promising target for pyroptotic tissue injury. Here, the authors show that methylcobalamin in base-off conformation coordinates to Cys180 in GSDME to prevent caspase-3/GzmB-GSDME interactions and thereby GSDME-mediated liver failure.

Although cyclopropanes are found in many natural products, agrochemicals, and pharmaceuticals, catalytic methods for cyclopropanation with two abundant substrates, mild conditions, high functional group tolerance, and broad scope are still highly desirable. Here, the authors report an intermolecular electrocatalytic cyclopropanation of alkenyl trifluoroborates with methylene compounds.

In 1972, Erich Clar envisioned Clar’s goblet, a polycyclic aromatic hydrocarbon featuring two unpaired electrons that are spin-paired. However, synthesizing it in a solution phase remains challenging. Now a derivative of Clar’s goblet has been prepared in solution, and spin entanglement at the molecular scale has been demonstrated experimentally.

Proposals for the realization of Weyl semimetals, topologically non-trivial materials which host Weyl fermion quasiparticles, have faced demanding experimental requirements. Here, the authors predict such a state in stoichiometric TaAs, arising due to the breaking of inversion symmetry.

By integrating the opposing effects through sediment and runoff changes, this study reveals that ecological restoration in the Yellow River Basin enhances hydropower potential, advancing our understanding of the ecosystem-water-sediment-energy nexus.

Metasurfaces offer an approach for computer generated holograms with good efficiency and ease of fabrication. Here, Ye et al.report on spin and wavelength multiplexed nonlinear metasurface holography, showing construction of holographic images using fundamental and harmonic generation waves of different spins.

Weyl particles are massless relativistic fermions recently observed in solid-state materials where they are characterized by Weyl points: topologically protected crossings in their band structure. Here, the authors demonstrate a novel type of plasmonic Weyl point in a magnetized plasma.

From 2000 to 2023, Northeast Asia saw a net loss of surface water in Far East Russia due to rising temperatures and evaporative demand, and a net gain in Northeast China driven by increased precipitation and irrigation infrastructure, according to integrated analysis of remote sensing, climate, and anthropogenic data.

The wide range of properties encountered in metamaterials make them promising for numerous optical applications. Chenet al. build a plasmonic flat metamaterial lens with an abrupt phase change that functions as a convex lens for one handedness of light and a concave lens for the other.

International shipping is a major emitter of greenhouse gases, but quantifying responsibilities has been difficult. This study uses satellite-observed data on vessels to determine the emissions from and subsequent health impacts of US–China bilateral trade of goods.

Hyperactivation of ribosome biogenesis (RiBi) causes excessive ribosome production, contributing to genome instability and cancer progression. The authors investigate the role of RiBPs in breast cancer, highlighting the upregulation of factors like DCAF13, which enhances cell proliferation by regulating Pol I transcription via K63-linked ubiquitination of RPA194.

Cancer resistance to apoptosis can hinder T-cell-based therapies. Here, the authors develop a temperature-sensitive system for the controlled delivery of a Cas9 gene-editing sequence targeting resistance mechanisms HSP70 and BAG3, which with a mild thermal effect increases T-cell delivery and therapeutic outcomes.

Aryl hydrocarbon receptor (AHR) is an emerging immune-related drug target. Here, the authors report the crystal structures of AHR with six agonists bound, revealing the molecular mechanisms of diverse ligand binding and allosteric activation of AHR.

Black holes are difficult to study experimentally, owing to their distance from us and indeed their very nature. A theoretical study suggests that optical metamaterials that exhibit behaviour that is reminiscent of that of black holes, could enable us to learn more about these and other astrophysical objects.

The feasibility of satellite-assisted quantum communication is demonstrated by a field test on the ground. To supress noise due to sunlight the wavelength of 1,550 nm is chosen, and spectrum and spatial filtering technology developed.

Researchers present the evidence and mechanism of distinct phase transformation pathways in MAX phases under ion irradiation, providing a new theory and predictive method for phase behavior based on composition, advancing understanding of materials in extreme conditions.