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Control of Endogenous Adenosine Triphosphatase Activity by Energy-Linked Pyridine Nucleotide Reduction in Mitochondria

BRITTON CHANCE
TAKERU ITO
Research14 Jul 1962
Nature

Volume: 195, P: 150-153
Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis

The authors establish the ChIP-CryoEM method, which combines chromatin immunopurification coupled with cryo-electron microscopy, to visualize native human RNAPII elongation complexes in action, with and without transcription elongation factors.

Tomoya Kujirai
Junko Kato
Hitoshi Kurumizaka
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-12
Blood DNA virome associates with autoimmune diseases and COVID-19

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Noah Sasa
Shohei Kojima
Yukinori Okada
ResearchOpen Access03 Jan 2025
Nature Genetics

Volume: 57, P: 65-79
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Qingbo S. Wang
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access22 Aug 2022
Nature Communications

Volume: 13, P: 1-19
DOCK2 is involved in the host genetics and biology of severe COVID-19

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Ho Namkoong
Ryuya Edahiro
Yukinori Okada
ResearchOpen Access08 Aug 2022
Nature

Volume: 609, P: 754-760
Oxidative (co)polymerization of dithiarubicene derivatives and electrochromic properties of narrow-bandgap conjugated polymers

The following diagram is the form for Graphical Abstract. The use of color to enhance quality and appearance is encouraged. The graphics should be EPS, PS, CDX, PPT, and TIFF formats at 300 dpi for color and 1200 dpi for black and white.

Koji Takagi
Takeru Yamamori
Kenji Tsukamoto
Research26 May 2022
Polymer Journal

Volume: 54, P: 1055-1062
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

Ryuya Edahiro
Yuya Shirai
Yukinori Okada
ResearchOpen Access24 Apr 2023
Nature Genetics

Volume: 55, P: 753-767
Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage

No reliable serum biomarker for diffuse alveolar damage, a poor prognosis subtype of drug-induced interstitial lung disease, is currently available. Here, the authors show stratifin/14-3-3σ in serum is a promising biomarker for diagnosis of this type of disease.

Noriaki Arakawa
Atsuhito Ushiki
Masayuki Hanaoka
ResearchOpen Access04 Oct 2022
Nature Communications

Volume: 13, P: 1-16
Multi-species coexistence in Lotka-Volterra competitive systems with crowding effects

Maica Krizna A. Gavina
Takeru Tahara
Jin Yoshimura
ResearchOpen Access19 Jan 2018
Scientific Reports

Volume: 8, P: 1-8
Asymptotic stability of a modified Lotka-Volterra model with small immigrations

Takeru Tahara
Maica Krizna Areja Gavina
Jin Yoshimura
ResearchOpen Access04 May 2018
Scientific Reports

Volume: 8, P: 1-7
Longitudinal study of central sensitization and chronic low back pain in a Japanese cohort during the COVID-19 pandemic

Shizumasa Murata
Hiroshi Hashizume
Hiroshi Yamada
ResearchOpen Access07 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
Cardiac dysfunction due to mitochondrial impairment assessed by human iPS cells caused by DNM1L mutations

Madori T. Osawa
Yasunori Fujita
Shigeaki Nonoyama
ResearchOpen Access23 Apr 2025
Pediatric Research

P: 1-12
Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer

Takeru Sugihara
Shunsuke Nakagawa
Takuya Ayabe
ResearchOpen Access22 Mar 2016
British Journal of Cancer

Volume: 114, P: 1012-1018
Electrospun poly(vinyl alcohol) nanofibers: effects of degree of hydrolysis and enhanced water stability

The effects of the degree of hydrolysis (DH) of poly(vinyl alcohol) (PVA) on electrospinning and water resistance of electrospun PVA/poly(acrylic acid) (PAA) composite fibers were explored. At a constant concentration of PVA solution (∼8wt%), the average diameter of electrospun PVA fibers increased with increasing DH. The water resistance of heat-treated PVA/ PAA composite fibers was dramatically enhanced, and was also affected by PAA weight fractions (φPAA) in PVA/PAA blend solutions.

Jong-Chul Park
Takeru Ito
Ick-Soo Kim
Research20 Jan 2010
Polymer Journal

Volume: 42, P: 273-276
Phylogenetic, population structure, and population demographic analyses reveal that Vicia sepium in Japan is native and not introduced

Ichiro Tamaki
Mizuo Mizuno
Emiko Harada
ResearchOpen Access25 Nov 2023
Scientific Reports

Volume: 13, P: 1-10
Close association between non-alcoholic fatty liver disease and ossification of the posterior longitudinal ligament of the spine

Tsutomu Endo
Yoshinao Koike
Masahiko Takahata
ResearchOpen Access31 Aug 2021
Scientific Reports

Volume: 11, P: 1-10

Search

Control of Endogenous Adenosine Triphosphatase Activity by Energy-Linked Pyridine Nucleotide Reduction in Mitochondria

Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis

Blood DNA virome associates with autoimmune diseases and COVID-19

The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force

DOCK2 is involved in the host genetics and biology of severe COVID-19

Oxidative (co)polymerization of dithiarubicene derivatives and electrochromic properties of narrow-bandgap conjugated polymers

Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity

Stratifin as a novel diagnostic biomarker in serum for diffuse alveolar damage

Multi-species coexistence in Lotka-Volterra competitive systems with crowding effects

Asymptotic stability of a modified Lotka-Volterra model with small immigrations

Longitudinal study of central sensitization and chronic low back pain in a Japanese cohort during the COVID-19 pandemic

Cardiac dysfunction due to mitochondrial impairment assessed by human iPS cells caused by DNM1L mutations

Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer

Electrospun poly(vinyl alcohol) nanofibers: effects of degree of hydrolysis and enhanced water stability

Phylogenetic, population structure, and population demographic analyses reveal that Vicia sepium in Japan is native and not introduced

Close association between non-alcoholic fatty liver disease and ossification of the posterior longitudinal ligament of the spine

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