Nature Search

A circuit from the ventral subiculum to anterior hypothalamic nucleus GABAergic neurons essential for anxiety-like behavioral avoidance

Anxiety is thought to be evolutionarily rooted in predator defense. Yan et al. show that GABAergic neurons in the anterior hypothalamic nucleus (AHN), a node in the predator defense network, play an essential role in anxiety-like behaviors.

Jing-Jing Yan
Xiao-Jing Ding
Xiao-Hong Xu
ResearchOpen Access03 Dec 2022
Nature Communications

Volume: 13, P: 1-16
Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway

Meng-jiao Zhou
Jia-jie Yang
Xiao-hong Chen
ResearchOpen Access06 Mar 2023
Experimental & Molecular Medicine

Volume: 55, P: 597-611
A natural allele of proteasome maturation factor improves rice resistance to multiple pathogens

Crops with broad-spectrum resistance to multiple diseases are highly desirable in agricultural production. This study reports a natural gene variant that produces a proteasome maturation factor and improves rice resistance to four notorious pathogens.

Xiao-Hong Hu
Shuai Shen
Jing Fan
Research16 Jan 2023
Nature Plants

Volume: 9, P: 228-237
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

Tumour-associated macrophages (TAMs) facilitate malignant growth of glioblastoma (GBM). Here, the authors show that TAMs support glioma stem cell renewal via paracrine signalling to the pleiotrophin receptor PTPRZ1 and that blocking this axis results in increased survival of tumour-bearing animals.

Yu Shi
Yi-Fang Ping
Xiu-Wu Bian
ResearchOpen Access01 Jun 2017
Nature Communications

Volume: 8, P: 1-17
Value of TIRADS, BSRTC and FNA-BRAF^V600E mutation analysis in differentiating high-risk thyroid nodules

Yu-zhi Zhang
Ting Xu
Xiao-hong Wu
ResearchOpen Access24 Nov 2015
Scientific Reports

Volume: 5, P: 1-8
Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

Jun Liu
Dan-Dan Li
Zhong Wang
ResearchOpen Access01 Sept 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-10
A cohort autopsy study defines COVID-19 systemic pathogenesis

Xiao-Hong Yao
Tao Luo
Xiu-Wu Bian
ResearchOpen Access16 Jun 2021
Cell Research

Volume: 31, P: 836-846
Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

Miao Zhao
Hui-Zhen Su
Wan-Jin Chen
ResearchOpen Access29 Nov 2022
Cell Discovery

Volume: 8, P: 1-17
EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma

Qu-Jing Gai
Zhen Fu
Yan Wang
ResearchOpen Access02 Feb 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-12
Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain

Fei-Cheng Yang
Chuan Wang
Yan Wang
Research28 Mar 2022
Laboratory Investigation

Volume: 102, P: 741-752
VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

Kai Zhou
Yue-Liang Yao
Yi-Fang Ping
ResearchOpen Access24 Sept 2018
Cell Death & Disease

Volume: 9, P: 1-14
Improving bowel preparation for colonoscopy with a smartphone application driven by artificial intelligence

Yan Zhu
Dan-Feng Zhang
Ping-Hong Zhou
ResearchOpen Access14 Mar 2023
npj Digital Medicine

Volume: 6, P: 1-9
Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma

Liang Yi
Zhi-hua Zhou
Xiu-wu Bian
Research27 Jul 2007
Modern Pathology

Volume: 20, P: 1061-1068
Autophagy-related protein MoAtg14 is involved in differentiation, development and pathogenicity in the rice blast fungus Magnaporthe oryzae

Xiao-Hong Liu
Ya-Hui Zhao
Fu-Cheng Lin
ResearchOpen Access09 Jan 2017
Scientific Reports

Volume: 7, P: 1-13
Correction: Corrigendum: Calpains are involved in asexual and sexual development, cell wall integrity and pathogenicity of the rice blast fungus

Xiao-Hong Liu
Guo-Ao Ning
Fu-Cheng Lin
Amendments and CorrectionsOpen Access27 Feb 2017
Scientific Reports

Volume: 7, P: 1
Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

Xiao-Hong Yao
Zhi-Cheng He
Xiu-Wu Bian
CorrespondenceOpen Access28 Apr 2020
Cell Research

Volume: 30, P: 541-543
COVID-19-associated monocytic encephalitis (CAME): histological and proteomic evidence from autopsy

Pei-Pei Zhang
Zhi-Cheng He
Xiu-Wu Bian
ResearchOpen Access06 Jan 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-11
Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria

Xiao-Qing Xie
Yi Yang
Xiu-Wu Bian
ResearchOpen Access10 Jan 2023
Cell Research

Volume: 33, P: 215-228
An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial)

Huai-Yu Wang
Sha Gong
Peng-Cheng He
ResearchOpen Access21 Nov 2022
Blood Cancer Journal

Volume: 12, P: 1-8
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling

In the glioma microenvironment, tumor-associated macrophages secrete large amounts of chemokine (C-C motif) ligand 8 CCL8, which contributes to pseudopodia formation of glioblastoma cells and promotes progression of glioma. CCL8 induces invasion and stem-like traits of glioblastoma cells via CCR1/ CCR5-mediated ERK1/2 activation.

Xiang Zhang
Lu Chen
Xiu-wu Bian
Research20 Nov 2019
Laboratory Investigation

Volume: 100, P: 619-629
RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3

In this study the authors show that Rac family small GTPase 1 (RAC1-GTP) is overexpressed in colorectal cancer (CRC) and promotes epithelial-mesenchymal transition-mediated invasion of CRC cells through activation of the STAT3 pathway. Overexpression of RAC1-GTP in CRCs correlates with tumor progression and recurrence of CRCs, and predicts poor prognosis of CRC patients.

Kai Zhou
Jun Rao
Yi-fang Ping
Research08 Jun 2018
Laboratory Investigation

Volume: 98, P: 989-998
Microvascular fractal dimension predicts prognosis and response to chemotherapy in glioblastoma: an automatic image analysis study

Cong Chen
Zhi-cheng He
Yi-fang Ping
Research15 May 2018
Laboratory Investigation

Volume: 98, P: 924-934
Epidemiological characteristics of nasopharyngeal Streptococcus pneumoniae strains among children with pneumonia in Chongqing, China

Yi-Yi Yu
Xiao-Hong Xie
En-Mei Liu
ResearchOpen Access01 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Calpains are involved in asexual and sexual development, cell wall integrity and pathogenicity of the rice blast fungus

Xiao-Hong Liu
Guo-Ao Ning
Fu-Cheng Lin
ResearchOpen Access09 Aug 2016
Scientific Reports

Volume: 6, P: 1-13
Tamoxifen enhances stemness and promotes metastasis of ERα36⁺ breast cancer by upregulating ALDH1A1 in cancer cells

Qiang Wang
Jun Jiang
Xiu-Wu Bian
ResearchOpen Access02 Feb 2018
Cell Research

Volume: 28, P: 336-358

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A circuit from the ventral subiculum to anterior hypothalamic nucleus GABAergic neurons essential for anxiety-like behavioral avoidance

Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway

A natural allele of proteasome maturation factor improves rice resistance to multiple pathogens

Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

Value of TIRADS, BSRTC and FNA-BRAF^V600E mutation analysis in differentiating high-risk thyroid nodules

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

A cohort autopsy study defines COVID-19 systemic pathogenesis

Loss of function of CMPK2 causes mitochondria deficiency and brain calcification

EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma

Inhibitory effects of temozolomide on glioma cells is sensitized by RSL3-induced ferroptosis but negatively correlated with expression of ferritin heavy chain 1 and ferritin light chain

VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells

Improving bowel preparation for colonoscopy with a smartphone application driven by artificial intelligence

Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma

Autophagy-related protein MoAtg14 is involved in differentiation, development and pathogenicity in the rice blast fungus Magnaporthe oryzae

Correction: Corrigendum: Calpains are involved in asexual and sexual development, cell wall integrity and pathogenicity of the rice blast fungus

Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

COVID-19-associated monocytic encephalitis (CAME): histological and proteomic evidence from autopsy

Targeting ATAD3A-PINK1-mitophagy axis overcomes chemoimmunotherapy resistance by redirecting PD-L1 to mitochondria

An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial)

CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling

RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3

Microvascular fractal dimension predicts prognosis and response to chemotherapy in glioblastoma: an automatic image analysis study

Epidemiological characteristics of nasopharyngeal Streptococcus pneumoniae strains among children with pneumonia in Chongqing, China

Calpains are involved in asexual and sexual development, cell wall integrity and pathogenicity of the rice blast fungus

Tamoxifen enhances stemness and promotes metastasis of ERα36⁺ breast cancer by upregulating ALDH1A1 in cancer cells

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